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Attributes

UniProt ID
O23254
Protein Name
Serine hydroxymethyltransferase 4
Ligand Name
METHOTREXATE
DrugBank ID
DB00563
PDB Ligand Accession
MTX
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FBOZXECLQNJBKD-ZDUSSCGKSA-N
SMILES
CN(Cc1cnc2c(n1)c(nc(n2)N)N)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 6SMR
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Color Legend
Unassigned regionsLigand / hetero atomse6smrA1e6smrA2e6smrB1e6smrB2e6smrC1e6smrC2e6smrD1e6smrD2
ECOD domains from experimental PDB structures interacting with ligand DB00563
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O23254DB00563MTX6smre6smrA1A:309-470
O23254DB00563MTX6smre6smrA2A:-2-308
O23254DB00563MTX6smre6smrB1B:309-471
O23254DB00563MTX6smre6smrB2B:0-308
O23254DB00563MTX6smre6smrC1C:0-308
O23254DB00563MTX6smre6smrD1D:0-308
O23254DB00563MTX6smre6smrD2D:309-470