Attributes
UniProt ID
Protein Name
Receptor-interacting serine/threonine-protein kinase 2
Ligand Name
4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
PIIVPMZRLRQOTG-UHFFFAOYSA-N
SMILES
CC(C)(C)S(=O)(=O)c1cn2c(cc1OCCN3CCN(CC3)C)ncc2c4cc(nc(c4)Cl)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 5W5O
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Color Legend
Unassigned regionsLigand / hetero atomse5w5oA1e5w5oB1e5w5oC1e5w5oD1e5w5oE1e5w5oF1e5w5oG1e5w5oH1e5w5oI1e5w5oJ1e5w5oK1e5w5oL1e5w5oM1e5w5oN1e5w5oO1e5w5oP1
ECOD domains from experimental PDB structures interacting with ligand 9XA
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| O43353 | n/a | 9XA | 5w5o | e5w5oA1 | A:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oB1 | B:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oC1 | C:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oD1 | D:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oE1 | E:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oF1 | F:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oG1 | G:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oH1 | H:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oI1 | I:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oJ1 | J:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oK1 | K:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oL1 | L:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oM1 | M:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oN1 | N:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oO1 | O:5-310 |
| O43353 | n/a | 9XA | 5w5o | e5w5oP1 | P:5-310 |