DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Orexin/Hypocretin receptor type 1
Ligand Name
(1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
MUGXRYIUWFITCP-PGRDOPGGSA-N
SMILES
Cc1c(cnc(n1)C)OCC2(CC2C(=O)Nc3ccc(cn3)F)c4cccc(c4)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 6TOT
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse6totA1e6totB1
ECOD domains from experimental PDB structures interacting with ligand DB11951
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O43613DB11951NRK6tote6totA1A:27-376
O43613DB11951NRK6tote6totB1B:43-377