DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK2
Ligand Name
3,5-diphenyl-2-(trifluoromethyl)-6~{H}-pyrazolo[1,5-a]pyrimidin-7-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QLWOIKQIMHVRGX-UHFFFAOYSA-N
SMILES
c1ccc(cc1)c2c(nn3c2N=C(CC3=O)c4ccccc4)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 8EX2
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse8ex2A1
ECOD domains from experimental PDB structures interacting with ligand Q2Q
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O60674n/aQ2Q8ex2e8ex2A1A:536-808