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Attributes

UniProt ID
O60674
Protein Name
Tyrosine-protein kinase JAK2
Ligand Name
(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
DrugBank ID
DB08877
PDB Ligand Accession
RXT
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
HFNKQEVNSGCOJV-OAHLLOKOSA-N
SMILES
c1c[nH]c2c1c(ncn2)c3cnn(c3)C(CC#N)C4CCCC4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 6VGL
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Color Legend
Unassigned regionsLigand / hetero atomse6vglA1e6vglB1e6vglC1e6vglD1
ECOD domains from experimental PDB structures interacting with ligand DB08877
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O60674DB08877RXT6vgle6vglA1A:828-1132
O60674DB08877RXT6vgle6vglB1B:835-1132
O60674DB08877RXT6vgle6vglC1C:843-1131
O60674DB08877RXT6vgle6vglD1D:843-1131
O60674DB08877RXT6vnke6vnkA1A:835-1132
O60674DB08877RXT6vnke6vnkB1B:835-1132
O60674DB08877RXT6vnke6vnkC1C:843-1131
O60674DB08877RXT6vnke6vnkD1D:843-1131
O60674DB08877RXT6wtne6wtnA1A:843-1135