NICKEL (II) ION

O75164 — Lysine-specific demethylase 4A demethylase 4A) demethylase 4A

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand NI

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand NI

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
O75164	n/a	2oq6	NI	A	501	e2oq6A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2oq6	NI	B	501	e2oq6B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2oq7	NI	A	501	e2oq7A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2oq7	NI	B	501	e2oq7B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2os2	NI	A	501	e2os2A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2os2	NI	B	501	e2os2B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ot7	NI	A	501	e2ot7A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ot7	NI	B	501	e2ot7B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ox0	NI	A	501	e2ox0A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ox0	NI	B	501	e2ox0B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2q8c	NI	A	501	e2q8cA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2q8c	NI	B	502	e2q8cB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2q8d	NI	A	501	e2q8dA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2q8d	NI	B	502	e2q8dB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2q8e	NI	A	501	e2q8eA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2q8e	NI	B	502	e2q8eB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2vd7	NI	A	501	e2vd7A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2vd7	NI	B	501	e2vd7B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2wwj	NI	A	501	e2wwjA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2wwj	NI	B	501	e2wwjB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ybk	NI	A	501	e2ybkA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ybk	NI	B	501	e2ybkB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ybp	NI	A	1356	e2ybpA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ybp	NI	B	1356	e2ybpB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ybs	NI	A	1356	e2ybsA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	2ybs	NI	B	1356	e2ybsB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3njy	NI	A	501	e3njyA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3njy	NI	B	501	e3njyB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3pdq	NI	A	501	e3pdqA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3pdq	NI	B	501	e3pdqB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3rvh	NI	A	501	e3rvhA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3rvh	NI	B	501	e3rvhB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3u4s	NI	A	501	e3u4sA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	3u4s	NI	B	501	e3u4sB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4ai9	NI	A	501	e4ai9A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4ai9	NI	B	501	e4ai9B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4bis	NI	A	501	e4bisA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4bis	NI	B	501	e4bisB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4gd4	NI	A	501	e4gd4A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4gd4	NI	B	501	e4gd4B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4ura	NI	A	2501	e4uraA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4ura	NI	B	2501	e4uraB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4v2v	NI	A	1357	e4v2vA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4v2v	NI	B	1356	e4v2vB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4v2w	NI	A	501	e4v2wA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	4v2w	NI	B	501	e4v2wB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5f5i	NI	A	501	e5f5iA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5f5i	NI	B	501	e5f5iB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	A	1362	e5fpvA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	B	1361	e5fpvB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	C	1361	e5fpvC1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	D	1362	e5fpvD1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	G	1360	e5fpvB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	G	1360	e5fpvG1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fpv	NI	H	1363	e5fpvH1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fwe	NI	A	1355	e5fweA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fwe	NI	B	1356	e5fweB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fy8	NI	A	501	e5fy8A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fy8	NI	B	501	e5fy8B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fyc	NI	A	501	e5fycA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fyc	NI	B	501	e5fycB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fyi	NI	A	501	e5fyiA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5fyi	NI	B	501	e5fyiB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly1	NI	A	501	e5ly1A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly1	NI	B	501	e5ly1B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly1	NI	C	402	e5ly1C1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly1	NI	D	501	e5ly1D1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly2	NI	A	501	e5ly2A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly2	NI	B	402	e5ly2B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly2	NI	C	501	e5ly2C1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5ly2	NI	D	402	e5ly2D1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5tvr	NI	A	401	e5tvrA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5tvr	NI	B	401	e5tvrB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5tvs	NI	A	401	e5tvsA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5tvs	NI	B	401	e5tvsB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vgi	NI	A	501	e5vgiA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vgi	NI	B	501	e5vgiB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vgi	NI	C	501	e5vgiC1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vgi	NI	D	501	e5vgiD1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vmp	NI	A	501	e5vmpA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vmp	NI	B	501	e5vmpB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vmp	NI	C	501	e5vmpC1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	5vmp	NI	D	501	e5vmpD1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg1	NI	A	501	e6cg1A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg1	NI	B	501	e6cg1B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg1	NI	C	501	e6cg1C1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg1	NI	D	501	e6cg1D1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg2	NI	A	501	e6cg2A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg2	NI	B	501	e6cg2B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg2	NI	C	501	e6cg2C1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6cg2	NI	D	501	e6cg2D1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6g5w	NI	A	403	e6g5wA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6g5w	NI	B	403	e6g5wA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6g5w	NI	B	403	e6g5wB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6g5x	NI	A	404	e6g5xA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6g5x	NI	B	402	e6g5xB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6h8p	NI	A	501	e6h8pA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	6h8p	NI	B	501	e6h8pB1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	7eqv	NI	A	402	e7eqvA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	8wd3	NI	A	501	e8wd3A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN
O75164	n/a	8wd3	NI	B	501	e8wd3B1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	JmjC,JmjN