DrugDomain logoDrugDomain

4-amino-N-(6-chloro-2-fluoro-3-{[(2-fluorophenyl)sulfonyl]amino}phenyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)quinazoline-8-carboxamide

O75460 — Serine/threonine-protein kinase/endoribonuclease IRE1

← Back

Attributes

UniProt ID
O75460
Protein Name
Serine/threonine-protein kinase/endoribonuclease IRE1
Ligand Name
4-amino-N-(6-chloro-2-fluoro-3-{[(2-fluorophenyl)sulfonyl]amino}phenyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)quinazoline-8-carboxamide
DrugBank ID
None
PDB Ligand Accession
N8S
ChEMBL ID
CHEMBL4752754
PubChem ID
155899127
InChIKey
SLZQHMNLJFHHQH-UHFFFAOYSA-N
SMILES
Cc1c(cn(n1)C)c2cc3c(c(c2)C(=O)Nc4c(ccc(c4F)NS(=O)(=O)c5ccccc5F)Cl)ncnc3N
Drug Action
No data available
Affinity Metrics
No affinity data available