DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Serine/threonine-protein kinase/endoribonuclease IRE1
Ligand Name
4-amino-N-(6-chloro-2-fluoro-3-{[(2-fluorophenyl)sulfonyl]amino}phenyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)quinazoline-8-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SLZQHMNLJFHHQH-UHFFFAOYSA-N
SMILES
Cc1c(cn(n1)C)c2cc3c(c(c2)C(=O)Nc4c(ccc(c4F)NS(=O)(=O)c5ccccc5F)Cl)ncnc3N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6XDB
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Color Legend
Unassigned regionsLigand / hetero atomse6xdbA1e6xdbA2
ECOD domains from experimental PDB structures interacting with ligand N8S
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O75460n/aN8S6xdbe6xdbA2A:561-832