DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Serine/threonine-protein kinase/endoribonuclease IRE1
Ligand Name
2-chloro-N-(6-methyl-5-{[3-(2-{[(3S)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XMWUCMFVDXDRDE-NRFANRHFSA-N
SMILES
Cc1ccc2c(c1Oc3c(cccn3)c4ccnc(n4)NC5CCCNC5)cccc2NS(=O)(=O)c6ccccc6Cl
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 6URC
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Color Legend
Unassigned regionsLigand / hetero atomse6urcA1e6urcA2e6urcB1e6urcB2
ECOD domains from experimental PDB structures interacting with ligand QFV
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O75460n/aQFV6urce6urcA2A:560-832
O75460n/aQFV6urce6urcB2B:560-832