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O75460 — Serine/threonine-protein kinase/endoribonuclease IRE1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB14546

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB14546

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O75460DB145463p23SO4A1003e3p23A1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
O75460DB145463p23SO4A1003e3p23C1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
O75460DB145464u6rSO4A1006e4u6rA2Four-helical up-and-down bundleHEPNNucleotidyltransferase substrate binding subunit/domainRibonuc_2-5A
O75460DB145464z7hSO4A1002e4z7hA2Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase