Attributes
UniProt ID
Protein Name
Isocitrate dehydrogenase cytoplasmic -specific ICDH
Ligand Name
(4S)-3-(2-{[(1S)-1-phenylethyl]amino}pyrimidin-4-yl)-4-(propan-2-yl)-1,3-oxazolidin-2-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
CUTPLPKYQGWUBC-DZGCQCFKSA-N
SMILES
CC(C)C1COC(=O)N1c2ccnc(n2)NC(C)c3ccccc3
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5SVF
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Color Legend
Unassigned regionsLigand / hetero atomse5svfA1e5svfA2e5svfB1e5svfB2e5svfC1e5svfC2e5svfD1e5svfD2
ECOD domains from experimental PDB structures interacting with ligand 70P
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| O75874 | n/a | 70P | 5svf | e5svfA1 | A:106-286 |
| O75874 | n/a | 70P | 5svf | e5svfA2 | A:4-105,A:287-412 |
| O75874 | n/a | 70P | 5svf | e5svfB1 | B:3-105,B:287-412 |
| O75874 | n/a | 70P | 5svf | e5svfB2 | B:106-286 |
| O75874 | n/a | 70P | 5svf | e5svfC1 | C:4-105,C:287-414 |
| O75874 | n/a | 70P | 5svf | e5svfC2 | C:106-286 |
| O75874 | n/a | 70P | 5svf | e5svfD1 | D:4-105,D:287-410 |
| O75874 | n/a | 70P | 5svf | e5svfD2 | D:106-286 |