Attributes
UniProt ID
Protein Name
Isocitrate dehydrogenase cytoplasmic -specific ICDH
Ligand Name
(4S)-3-[2-({(1S)-1-[5-(4-fluoro-3-methylphenyl)pyrimidin-2-yl]ethyl}amino)pyrimidin-4-yl]-4-(propan-2-yl)-1,3-oxazolidin-2-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JDCYIMQAIKEACU-HNAYVOBHSA-N
SMILES
Cc1cc(ccc1F)c2cnc(nc2)C(C)Nc3nccc(n3)N4C(COC4=O)C(C)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5TQH
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Color Legend
Unassigned regionsLigand / hetero atomse5tqhA1e5tqhA2e5tqhB1e5tqhB2e5tqhC1e5tqhC2e5tqhD1e5tqhD2
ECOD domains from experimental PDB structures interacting with ligand 7J2
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| O75874 | n/a | 7J2 | 5tqh | e5tqhA1 | A:3-105,A:287-412 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhA2 | A:106-286 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhB1 | B:106-286 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhB2 | B:3-105,B:287-412 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhC1 | C:106-286 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhC2 | C:3-105,C:287-414 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhD1 | D:4-105,D:287-412 |
| O75874 | n/a | 7J2 | 5tqh | e5tqhD2 | D:106-286 |