DrugDomain logoDrugDomain

Attributes

UniProt ID
O75874
Protein Name
Isocitrate dehydrogenase cytoplasmic -specific ICDH
Ligand Name
2-OXOGLUTARIC ACID
DrugBank ID
DB08845
PDB Ligand Accession
AKG
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
C(CC(=O)O)C(=O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 3INM
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Color Legend
Unassigned regionsLigand / hetero atomse3inmA1e3inmA2e3inmB1e3inmB2e3inmC1e3inmC2
ECOD domains from experimental PDB structures interacting with ligand DB08845
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O75874DB08845AKG3inme3inmA1A:106-286
O75874DB08845AKG3inme3inmA2A:4-105,A:287-410
O75874DB08845AKG3inme3inmB1B:106-286
O75874DB08845AKG3inme3inmB2B:4-105,B:287-414
O75874DB08845AKG3inme3inmC1C:4-105,C:287-410
O75874DB08845AKG3inme3inmC2C:106-286
O75874DB08845AKG4kzoe4kzoA1A:106-286
O75874DB08845AKG4kzoe4kzoA2A:3-105,A:287-416
O75874DB08845AKG4kzoe4kzoB1B:3-105,B:287-414
O75874DB08845AKG4kzoe4kzoB2B:106-286
O75874DB08845AKG4kzoe4kzoC1C:4-105,C:287-413
O75874DB08845AKG4kzoe4kzoC2C:106-286
O75874DB08845AKG4l03e4l03A1A:3-105,A:287-418
O75874DB08845AKG4l03e4l03A2A:106-286
O75874DB08845AKG4l03e4l03B1B:106-286
O75874DB08845AKG4l03e4l03B2B:3-105,B:287-414
O75874DB08845AKG4l03e4l03C1C:106-286
O75874DB08845AKG4l03e4l03C2C:3-105,C:287-419
O75874DB08845AKG4l04e4l04A1A:5-105,A:287-415
O75874DB08845AKG4l04e4l04A2A:106-286
O75874DB08845AKG4l04e4l04B1B:3-105,B:287-414
O75874DB08845AKG4l04e4l04B2B:106-286
O75874DB08845AKG4l04e4l04C1C:106-286
O75874DB08845AKG4l04e4l04C2C:4-105,C:287-415
O75874DB08845AKG4l04e4l04D1D:106-286
O75874DB08845AKG4l04e4l04D2D:3-105,D:287-414
O75874DB08845AKG4l04e4l04E1E:4-105,E:287-415
O75874DB08845AKG4l04e4l04E2E:106-286
O75874DB08845AKG4l04e4l04F1F:106-286
O75874DB08845AKG4l04e4l04F2F:3-105,F:287-414
O75874DB08845AKG4l06e4l06A1A:106-286
O75874DB08845AKG4l06e4l06A2A:3-105,A:287-415
O75874DB08845AKG4l06e4l06B1B:106-286
O75874DB08845AKG4l06e4l06B2B:3-105,B:287-414
O75874DB08845AKG4l06e4l06C1C:106-286
O75874DB08845AKG4l06e4l06C2C:3-105,C:287-413
O75874DB08845AKG4l06e4l06D1D:106-286
O75874DB08845AKG4l06e4l06D2D:4-105,D:287-414
O75874DB08845AKG4l06e4l06E1E:106-286
O75874DB08845AKG4l06e4l06E2E:3-105,E:287-415
O75874DB08845AKG4l06e4l06F1F:3-105,F:287-414
O75874DB08845AKG4l06e4l06F2F:106-286
O75874DB08845AKG7pjme7pjmA1A:3-105,A:287-417
O75874DB08845AKG7pjme7pjmA2A:106-286
O75874DB08845AKG7pjme7pjmB1B:106-286
O75874DB08845AKG7pjme7pjmB2B:2-105,B:287-413
O75874DB08845AKG7pjme7pjmC1C:3-105,C:287-416
O75874DB08845AKG7pjme7pjmC2C:106-286