DrugDomain

Attributes

UniProt ID

O75874

Protein Name

Isocitrate dehydrogenase cytoplasmic -specific ICDH

Ligand Name

ISOCITRIC ACID

DrugBank ID

None

PDB Ligand Accession

ICT

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

ODBLHEXUDAPZAU-ZAFYKAAXSA-N

SMILES

C(C(C(C(=O)O)O)C(=O)O)C(=O)O

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

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Mol*

Structure: 1T0L

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Color Legend

Unassigned regionsLigand / hetero atomse1t0lA1e1t0lA2e1t0lB1e1t0lB2e1t0lC1e1t0lC2e1t0lD1e1t0lD2

ECOD domains from experimental PDB structures interacting with ligand ICT

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
O75874	n/a	ICT	1t0l	e1t0lA1	A:106-286
O75874	n/a	ICT	1t0l	e1t0lA2	A:1-105,A:287-414
O75874	n/a	ICT	1t0l	e1t0lB1	B:106-286
O75874	n/a	ICT	1t0l	e1t0lB2	B:1-105,B:287-414
O75874	n/a	ICT	1t0l	e1t0lC1	C:106-286
O75874	n/a	ICT	1t0l	e1t0lC2	C:1-105,C:287-414
O75874	n/a	ICT	1t0l	e1t0lD1	D:106-286
O75874	n/a	ICT	1t0l	e1t0lD2	D:1-105,D:287-414
O75874	n/a	ICT	3map	e3mapA1	A:106-286
O75874	n/a	ICT	3map	e3mapA2	A:3-105,A:287-413
O75874	n/a	ICT	3map	e3mapB1	B:3-105,B:287-413
O75874	n/a	ICT	3map	e3mapB2	B:106-286
O75874	n/a	ICT	3mas	e3masA2	A:3-105,A:287-414
O75874	n/a	ICT	3mas	e3masB2	B:3-105,B:287-413
O75874	n/a	ICT	5yfn	e5yfnA1	A:106-286
O75874	n/a	ICT	5yfn	e5yfnA2	A:-6-105,A:287-411
O75874	n/a	ICT	5yfn	e5yfnB1	B:-6-105,B:287-412
O75874	n/a	ICT	5yfn	e5yfnB2	B:106-286
O75874	n/a	ICT	6bkx	e6bkxA1	A:3-105,A:287-416
O75874	n/a	ICT	6bkx	e6bkxA2	A:106-286
O75874	n/a	ICT	6bkx	e6bkxB2	B:106-286
O75874	n/a	ICT	6bkx	e6bkxC1	C:3-105,C:287-419
O75874	n/a	ICT	6bkx	e6bkxC2	C:106-286
O75874	n/a	ICT	6bl0	e6bl0A1	A:106-286
O75874	n/a	ICT	6bl0	e6bl0A2	A:3-105,A:287-418
O75874	n/a	ICT	6bl0	e6bl0B1	B:3-105,B:287-418
O75874	n/a	ICT	6bl0	e6bl0B2	B:106-286
O75874	n/a	ICT	6bl0	e6bl0C1	C:106-286
O75874	n/a	ICT	6bl0	e6bl0C2	C:3-105,C:287-418
O75874	n/a	ICT	6bl1	e6bl1A1	A:106-286
O75874	n/a	ICT	6bl1	e6bl1A2	A:3-105,A:287-418
O75874	n/a	ICT	6bl1	e6bl1B2	B:106-286
O75874	n/a	ICT	6bl1	e6bl1C1	C:3-105,C:287-418
O75874	n/a	ICT	6bl1	e6bl1C2	C:106-286
O75874	n/a	ICT	6bl2	e6bl2A1	A:3-105,A:287-418
O75874	n/a	ICT	6bl2	e6bl2A2	A:106-286
O75874	n/a	ICT	6bl2	e6bl2B1	B:3-105,B:287-418
O75874	n/a	ICT	6bl2	e6bl2B2	B:106-286
O75874	n/a	ICT	6bl2	e6bl2C1	C:106-286
O75874	n/a	ICT	6bl2	e6bl2C2	C:3-105,C:287-418
O75874	n/a	ICT	6pay	e6payA1	A:106-286
O75874	n/a	ICT	6pay	e6payA2	A:4-105,A:287-412
O75874	n/a	ICT	6pay	e6payB1	B:3-105,B:287-414
O75874	n/a	ICT	6pay	e6payB2	B:106-286
O75874	n/a	ICT	6pay	e6payC1	C:5-105,C:287-412
O75874	n/a	ICT	6pay	e6payC2	C:106-286
O75874	n/a	ICT	6pay	e6payD1	D:106-286
O75874	n/a	ICT	6pay	e6payD2	D:5-105,D:287-412