DrugDomain logoDrugDomain

Attributes

UniProt ID
O75874
Protein Name
Isocitrate dehydrogenase cytoplasmic -specific ICDH
Ligand Name
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB03461
PDB Ligand Accession
NAP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 1T09
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Color Legend
Unassigned regionsLigand / hetero atomse1t09A1e1t09A2e1t09B1e1t09B2
ECOD domains from experimental PDB structures interacting with ligand DB03461
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O75874DB03461NAP1t09e1t09A1A:106-286
O75874DB03461NAP1t09e1t09A2A:1-105,A:287-414
O75874DB03461NAP1t09e1t09B1B:1-105,B:287-414
O75874DB03461NAP1t09e1t09B2B:106-286
O75874DB03461NAP1t0le1t0lA1A:106-286
O75874DB03461NAP1t0le1t0lA2A:1-105,A:287-414
O75874DB03461NAP1t0le1t0lB1B:106-286
O75874DB03461NAP1t0le1t0lB2B:1-105,B:287-414
O75874DB03461NAP1t0le1t0lC1C:106-286
O75874DB03461NAP1t0le1t0lC2C:1-105,C:287-414
O75874DB03461NAP1t0le1t0lD1D:106-286
O75874DB03461NAP1t0le1t0lD2D:1-105,D:287-414
O75874DB03461NAP3mape3mapA1A:106-286
O75874DB03461NAP3mape3mapA2A:3-105,A:287-413
O75874DB03461NAP3mape3mapB1B:3-105,B:287-413
O75874DB03461NAP3mape3mapB2B:106-286
O75874DB03461NAP3mare3marA1A:2-105,A:287-414
O75874DB03461NAP3mare3marB1B:1-105,B:287-414
O75874DB03461NAP3mase3masA1A:106-286
O75874DB03461NAP3mase3masA2A:3-105,A:287-414
O75874DB03461NAP3mase3masB2B:3-105,B:287-413
O75874DB03461NAP4kzoe4kzoA1A:106-286
O75874DB03461NAP4kzoe4kzoA2A:3-105,A:287-416
O75874DB03461NAP4kzoe4kzoB1B:3-105,B:287-414
O75874DB03461NAP4kzoe4kzoB2B:106-286
O75874DB03461NAP4kzoe4kzoC1C:4-105,C:287-413
O75874DB03461NAP4l03e4l03A1A:3-105,A:287-418
O75874DB03461NAP4l03e4l03A2A:106-286
O75874DB03461NAP4l03e4l03B1B:106-286
O75874DB03461NAP4l03e4l03B2B:3-105,B:287-414
O75874DB03461NAP4l03e4l03C2C:3-105,C:287-419
O75874DB03461NAP4l04e4l04A1A:5-105,A:287-415
O75874DB03461NAP4l04e4l04A2A:106-286
O75874DB03461NAP4l04e4l04B1B:3-105,B:287-414
O75874DB03461NAP4l04e4l04B2B:106-286
O75874DB03461NAP4l04e4l04C1C:106-286
O75874DB03461NAP4l04e4l04C2C:4-105,C:287-415
O75874DB03461NAP4l04e4l04D1D:106-286
O75874DB03461NAP4l04e4l04D2D:3-105,D:287-414
O75874DB03461NAP4l04e4l04E1E:4-105,E:287-415
O75874DB03461NAP4l04e4l04E2E:106-286
O75874DB03461NAP4l04e4l04F1F:106-286
O75874DB03461NAP4l04e4l04F2F:3-105,F:287-414
O75874DB03461NAP4l06e4l06A1A:106-286
O75874DB03461NAP4l06e4l06A2A:3-105,A:287-415
O75874DB03461NAP4l06e4l06B1B:106-286
O75874DB03461NAP4l06e4l06B2B:3-105,B:287-414
O75874DB03461NAP4l06e4l06C1C:106-286
O75874DB03461NAP4l06e4l06C2C:3-105,C:287-413
O75874DB03461NAP4l06e4l06D1D:106-286
O75874DB03461NAP4l06e4l06D2D:4-105,D:287-414
O75874DB03461NAP4l06e4l06E1E:106-286
O75874DB03461NAP4l06e4l06E2E:3-105,E:287-415
O75874DB03461NAP4l06e4l06F1F:3-105,F:287-414
O75874DB03461NAP4l06e4l06F2F:106-286
O75874DB03461NAP4umxe4umxA1A:3-105,A:287-414
O75874DB03461NAP4umxe4umxA2A:106-286
O75874DB03461NAP4umxe4umxB2B:3-105,B:287-414
O75874DB03461NAP4umye4umyA2A:3-105,A:287-413
O75874DB03461NAP4umye4umyB1B:3-105,B:287-413
O75874DB03461NAP4xs3e4xs3A1A:3-105,A:287-412
O75874DB03461NAP4xs3e4xs3A2A:106-286
O75874DB03461NAP4xs3e4xs3B1B:106-286
O75874DB03461NAP4xs3e4xs3B2B:4-105,B:287-413
O75874DB03461NAP5de1e5de1A1A:3-105,A:287-414
O75874DB03461NAP5de1e5de1A2A:106-286
O75874DB03461NAP5de1e5de1B1B:3-105,B:287-413
O75874DB03461NAP5lgee5lgeA1A:3-105,A:287-416
O75874DB03461NAP5lgee5lgeB1B:3-105,B:287-416
O75874DB03461NAP5lgee5lgeB2B:106-286
O75874DB03461NAP5lgee5lgeC2C:2-105,C:287-416
O75874DB03461NAP5lgee5lgeD1D:106-286
O75874DB03461NAP5lgee5lgeD2D:3-105,D:287-415
O75874DB03461NAP5yfme5yfmA1A:3-105,A:287-411
O75874DB03461NAP5yfme5yfmB1B:3-105,B:287-411
O75874DB03461NAP5yfme5yfmC1C:4-105,C:287-411
O75874DB03461NAP6bkze6bkzA1A:106-286
O75874DB03461NAP6bkze6bkzA2A:3-105,A:287-414
O75874DB03461NAP6bkze6bkzB1B:3-105,B:287-414
O75874DB03461NAP6bkze6bkzB2B:106-286
O75874DB03461NAP6bl0e6bl0A1A:106-286
O75874DB03461NAP6bl0e6bl0A2A:3-105,A:287-418
O75874DB03461NAP6bl0e6bl0B1B:3-105,B:287-418
O75874DB03461NAP6bl0e6bl0B2B:106-286
O75874DB03461NAP6bl0e6bl0C1C:106-286
O75874DB03461NAP6bl0e6bl0C2C:3-105,C:287-418
O75874DB03461NAP6o2ye6o2yA1A:3-105,A:287-415
O75874DB03461NAP6o2ye6o2yA2A:106-286
O75874DB03461NAP6o2ye6o2yB1B:106-286
O75874DB03461NAP6o2ye6o2yB2B:4-105,B:287-414
O75874DB03461NAP6o2ye6o2yC1C:4-105,C:287-414
O75874DB03461NAP6o2ye6o2yC2C:106-286
O75874DB03461NAP6o2ze6o2zA1A:106-286
O75874DB03461NAP6o2ze6o2zA2A:3-105,A:287-415
O75874DB03461NAP6o2ze6o2zB1B:106-286
O75874DB03461NAP6o2ze6o2zB2B:3-105,B:287-415
O75874DB03461NAP6u4je6u4jA1A:3-105,A:287-417
O75874DB03461NAP6u4je6u4jA2A:106-286
O75874DB03461NAP6u4je6u4jB1B:3-105,B:287-414
O75874DB03461NAP6u4je6u4jB2B:106-286