DrugDomain logoDrugDomain

Attributes

UniProt ID
O75874
Protein Name
Isocitrate dehydrogenase cytoplasmic -specific ICDH
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 3INM
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse3inmA1e3inmA2e3inmB1e3inmB2e3inmC1e3inmC2
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O75874DB02338NDP3inme3inmA1A:106-286
O75874DB02338NDP3inme3inmA2A:4-105,A:287-410
O75874DB02338NDP3inme3inmB1B:106-286
O75874DB02338NDP3inme3inmB2B:4-105,B:287-414
O75874DB02338NDP3inme3inmC1C:4-105,C:287-410
O75874DB02338NDP4i3ke4i3kA1A:4-105,A:287-411
O75874DB02338NDP4i3ke4i3kB2B:4-105,B:287-411
O75874DB02338NDP4i3le4i3lA2A:4-105,A:287-411
O75874DB02338NDP4i3le4i3lB1B:4-105,B:287-411
O75874DB02338NDP4xrxe4xrxA1A:3-105,A:287-413
O75874DB02338NDP4xrxe4xrxA2A:106-286
O75874DB02338NDP4xrxe4xrxB1B:106-286
O75874DB02338NDP4xrxe4xrxB2B:3-105,B:287-412
O75874DB02338NDP5k10e5k10A1A:3-105,A:287-413
O75874DB02338NDP5k10e5k10B2B:3-105,B:287-413
O75874DB02338NDP5k11e5k11A1A:3-105,A:287-413
O75874DB02338NDP5k11e5k11B2B:3-105,B:287-413
O75874DB02338NDP5l57e5l57A1A:3-105,A:287-414
O75874DB02338NDP5l57e5l57A2A:106-286
O75874DB02338NDP5l58e5l58A1A:3-105,A:287-414
O75874DB02338NDP5l58e5l58A2A:106-286
O75874DB02338NDP5sune5sunA1A:106-286
O75874DB02338NDP5sune5sunA2A:3-105,A:287-413
O75874DB02338NDP5sune5sunB1B:106-286
O75874DB02338NDP5sune5sunB2B:3-105,B:287-412
O75874DB02338NDP5svfe5svfA1A:106-286
O75874DB02338NDP5svfe5svfA2A:4-105,A:287-412
O75874DB02338NDP5svfe5svfB1B:3-105,B:287-412
O75874DB02338NDP5svfe5svfB2B:106-286
O75874DB02338NDP5svfe5svfC1C:4-105,C:287-414
O75874DB02338NDP5svfe5svfC2C:106-286
O75874DB02338NDP5svfe5svfD1D:4-105,D:287-410
O75874DB02338NDP5svfe5svfD2D:106-286
O75874DB02338NDP5tqhe5tqhA1A:3-105,A:287-412
O75874DB02338NDP5tqhe5tqhA2A:106-286
O75874DB02338NDP5tqhe5tqhB1B:106-286
O75874DB02338NDP5tqhe5tqhB2B:3-105,B:287-412
O75874DB02338NDP5tqhe5tqhC1C:106-286
O75874DB02338NDP5tqhe5tqhC2C:3-105,C:287-414
O75874DB02338NDP5tqhe5tqhD1D:4-105,D:287-412
O75874DB02338NDP5tqhe5tqhD2D:106-286
O75874DB02338NDP6adge6adgA2A:3-105,A:287-414
O75874DB02338NDP6adge6adgB1B:3-105,B:287-413
O75874DB02338NDP6b0ze6b0zA1A:106-286
O75874DB02338NDP6b0ze6b0zA2A:3-105,A:287-412
O75874DB02338NDP6b0ze6b0zB1B:106-286
O75874DB02338NDP6b0ze6b0zB2B:3-105,B:287-413
O75874DB02338NDP6b0ze6b0zC1C:106-286
O75874DB02338NDP6b0ze6b0zC2C:3-105,C:287-414
O75874DB02338NDP6b0ze6b0zD1D:3-105,D:287-411
O75874DB02338NDP6b0ze6b0zD2D:106-286
O75874DB02338NDP6io0e6io0A1A:106-286
O75874DB02338NDP6io0e6io0A2A:3-105,A:287-413
O75874DB02338NDP6io0e6io0B1B:3-105,B:287-412
O75874DB02338NDP6io0e6io0B2B:106-286
O75874DB02338NDP6paye6payA1A:106-286
O75874DB02338NDP6paye6payA2A:4-105,A:287-412
O75874DB02338NDP6paye6payD1D:106-286
O75874DB02338NDP6veie6veiA1A:3-105,A:287-415
O75874DB02338NDP6veie6veiA2A:106-286
O75874DB02338NDP6veie6veiB1B:3-105,B:287-419
O75874DB02338NDP6veie6veiB2B:106-286
O75874DB02338NDP6vg0e6vg0A1A:2-105,A:287-414
O75874DB02338NDP6vg0e6vg0B2B:2-105,B:287-416
O75874DB02338NDP6vg0e6vg0C1C:5-105,C:287-411
O75874DB02338NDP7pjme7pjmA1A:3-105,A:287-417
O75874DB02338NDP7pjme7pjmA2A:106-286
O75874DB02338NDP7pjme7pjmB1B:106-286
O75874DB02338NDP7pjme7pjmB2B:2-105,B:287-413
O75874DB02338NDP7pjme7pjmC1C:3-105,C:287-416
O75874DB02338NDP7pjme7pjmC2C:106-286
O75874DB02338NDP7pjne7pjnA1A:106-286
O75874DB02338NDP7pjne7pjnA2A:3-105,A:287-412
O75874DB02338NDP7pjne7pjnB1B:106-286
O75874DB02338NDP7pjne7pjnB2B:2-105,B:287-411
O75874DB02338NDP7pjne7pjnC1C:3-105,C:287-415
O75874DB02338NDP7pjne7pjnC2C:106-286
O75874DB02338NDP7pjne7pjnD1D:106-286
O75874DB02338NDP7pjne7pjnD2D:2-105,D:287-413
O75874DB02338NDP8baye8bayA1A:106-286
O75874DB02338NDP8baye8bayA2A:3-105,A:287-416
O75874DB02338NDP8baye8bayB1B:3-105,B:287-415
O75874DB02338NDP8baye8bayB2B:106-286
O75874DB02338NDP8baye8bayC2C:3-105,C:287-417
O75874DB02338NDP8hb9e8hb9AAA1AAA:106-286
O75874DB02338NDP8hb9e8hb9AAA2AAA:3-105,AAA:287-412
O75874DB02338NDP8hb9e8hb9BBB1BBB:3-105,BBB:287-412
O75874DB02338NDP8hb9e8hb9BBB2BBB:106-286
O75874DB02338NDP8hb9e8hb9CCC1CCC:3-105,CCC:287-412
O75874DB02338NDP8hb9e8hb9CCC2CCC:106-286
O75874DB02338NDP8hb9e8hb9DDD1DDD:1-105,DDD:287-411