Attributes
UniProt ID
Protein Name
cGMP-specific 3',5'-cyclic phosphodiesterase
Ligand Name
5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BNRNXUUZRGQAQC-UHFFFAOYSA-N
SMILES
CCCc1c2c(n(n1)C)C(=O)NC(=N2)c3cc(ccc3OCC)S(=O)(=O)N4CCN(CC4)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1TBF
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Color Legend
Unassigned regionsLigand / hetero atomse1tbfA1
ECOD domains from experimental PDB structures interacting with ligand DB00203
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| O76074 | DB00203 | VIA | 1tbf | e1tbfA1 | A:534-858 |
| O76074 | DB00203 | VIA | 1udt | e1udtA1 | A:537-858 |
| O76074 | DB00203 | VIA | 2h42 | e2h42A1 | A:535-858 |
| O76074 | DB00203 | VIA | 2h42 | e2h42B1 | B:535-858 |
| O76074 | DB00203 | VIA | 2h42 | e2h42C1 | C:535-858 |
| O76074 | DB00203 | VIA | 3jwq | e3jwqA1 | A:536-859 |
| O76074 | DB00203 | VIA | 3jwq | e3jwqB1 | B:536-859 |
| O76074 | DB00203 | VIA | 3jwq | e3jwqC1 | C:533-859 |
| O76074 | DB00203 | VIA | 3jwq | e3jwqD1 | D:537-859 |