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FLAVIN-ADENINE DINUCLEOTIDE

O89049 — Thioredoxin reductase 1, cytoplasmic

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03147

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03147

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O89049DB031471h6vFADA600e1h6vA1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADA600e1h6vA2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADA600e1h6vA3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031471h6vFADA600e1h6vB1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADB600e1h6vA1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADB600e1h6vA2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADB600e1h6vB1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADB600e1h6vB2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADB600e1h6vB3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031471h6vFADC600e1h6vC1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADC600e1h6vC2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADC600e1h6vC3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031471h6vFADC600e1h6vD1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADD600e1h6vC1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADD600e1h6vD1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADD600e1h6vD2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADD600e1h6vD3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031471h6vFADE600e1h6vE1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADE600e1h6vE2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADE600e1h6vE3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031471h6vFADE600e1h6vF1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADF600e1h6vE1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADF600e1h6vE2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADF600e1h6vE3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031471h6vFADF600e1h6vF1FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031471h6vFADF600e1h6vF2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031471h6vFADF600e1h6vF3Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADA600e3eanA4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADA600e3eanA5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADA600e3eanA6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADA600e3eanB6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADB600e3eanA4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADB600e3eanA6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADB600e3eanB4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADB600e3eanB5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADB600e3eanB6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADC600e3eanC4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADC600e3eanC5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADC600e3eanC6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADC600e3eanD6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADD600e3eanC6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADD600e3eanD4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADD600e3eanD5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADD600e3eanD6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADE600e3eanE4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADE600e3eanE5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADE600e3eanE6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADE600e3eanF6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADF600e3eanE4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADF600e3eanE5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADF600e3eanE6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eanFADF600e3eanF4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eanFADF600e3eanF5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eanFADF600e3eanF6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADA600e3eaoA4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADA600e3eaoA5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADA600e3eaoA6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADA600e3eaoB6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADB600e3eaoA4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADB600e3eaoA6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADB600e3eaoB4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADB600e3eaoB5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADB600e3eaoB6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADC600e3eaoC4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADC600e3eaoC5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADC600e3eaoC6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADC600e3eaoD6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADD600e3eaoC6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADD600e3eaoD4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADD600e3eaoD5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADD600e3eaoD6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADE600e3eaoE4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADE600e3eaoE5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADE600e3eaoE6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADE600e3eaoF6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADF600e3eaoE4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADF600e3eaoE5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADF600e3eaoE6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031473eaoFADF600e3eaoF4Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031473eaoFADF600e3eaoF5Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031473eaoFADF600e3eaoF6FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADA504e4kprA1Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031474kprFADA504e4kprA2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031474kprFADA504e4kprA3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADA504e4kprB3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADB502e4kprA2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031474kprFADB502e4kprA3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADB502e4kprB1Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031474kprFADB502e4kprB2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031474kprFADB502e4kprB3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADE505e4kprE1Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031474kprFADE505e4kprE2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031474kprFADE505e4kprE3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADE505e4kprF3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADF505e4kprE1Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031474kprFADF505e4kprE2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031474kprFADF505e4kprE3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim
O89049DB031474kprFADF505e4kprF1Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox
O89049DB031474kprFADF505e4kprF2Rossmann-likeRossmann-relatedFAD/NAD(P)-binding domainPyr_redox_2
O89049DB031474kprFADF505e4kprF3FAD-linked reductases, C-terminal domain-likeFAD/NAD-linked reduatases, dimerisation (C-terminal) domainFAD/NAD-linked reduatases, dimerisation (C-terminal) domainPyr_redox_dim