DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Glutaminase kidney isoform, mitochondrial
Ligand Name
2-cyclopropyl-N-{5-[4-({5-[(cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JHCGNAVCXZTYNC-UHFFFAOYSA-N
SMILES
C1CC1CC(=O)Nc2nnc(s2)N3CCC(CC3)Oc4nnc(s4)NC(=O)CC5CC5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6ULA
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Color Legend
Unassigned regionsLigand / hetero atomse6ulaA1e6ulaA2e6ulaA3e6ulaB1e6ulaB2e6ulaB3e6ulaC1e6ulaC2e6ulaC3e6ulaD1e6ulaD2e6ulaD3e6ulaE1e6ulaE2e6ulaE3e6ulaF1e6ulaF2e6ulaF3e6ulaG1e6ulaG2e6ulaG3e6ulaH1e6ulaH2e6ulaH3
ECOD domains from experimental PDB structures interacting with ligand QA4
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O94925n/aQA46ulae6ulaA1A:282-420
O94925n/aQA46ulae6ulaB3B:282-420
O94925n/aQA46ulae6ulaC3C:282-420
O94925n/aQA46ulae6ulaD2D:282-420
O94925n/aQA46ulae6ulaE1E:282-420
O94925n/aQA46ulae6ulaF1F:282-420
O94925n/aQA46ulae6ulaG3G:282-420
O94925n/aQA46ulae6ulaH2H:282-420