DrugDomain logoDrugDomain

Attributes

UniProt ID
O95831
Protein Name
Apoptosis-inducing factor 1, mitochondrial
Ligand Name
FLAVIN-ADENINE DINUCLEOTIDE
DrugBank ID
DB03147
PDB Ligand Accession
FAD
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VWWQXMAJTJZDQX-UYBVJOGSSA-N
SMILES
Cc1cc2c(cc1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)n5cnc6c5ncnc6N)O)O)O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 1M6I
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Color Legend
Unassigned regionsLigand / hetero atomse1m6iA1e1m6iA2e1m6iA3
ECOD domains from experimental PDB structures interacting with ligand DB03147
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O95831DB03147FAD1m6ie1m6iA1A:478-539,A:560-608
O95831DB03147FAD1m6ie1m6iA2A:128-263,A:401-477
O95831DB03147FAD1m6ie1m6iA3A:264-400
O95831DB03147FAD4bure4burA1A:262-398
O95831DB03147FAD4bure4burA2A:476-516,A:551-611
O95831DB03147FAD4bure4burA3A:128-261,A:399-475
O95831DB03147FAD4bure4burB1B:262-398
O95831DB03147FAD4bure4burB2B:476-516,B:553-610
O95831DB03147FAD4bure4burB3B:125-261,B:399-475
O95831DB03147FAD4bure4burC1C:478-517,C:558-612
O95831DB03147FAD4bure4burC2C:263-401
O95831DB03147FAD4bure4burC3C:127-263,C:401-477
O95831DB03147FAD4bure4burD1D:478-509,D:559-611
O95831DB03147FAD4bure4burD2D:128-263,D:401-477
O95831DB03147FAD4bure4burD3D:264-400
O95831DB03147FAD4bv6e4bv6A1A:263-400
O95831DB03147FAD4bv6e4bv6A2A:127-262,A:400-477
O95831DB03147FAD4bv6e4bv6A3A:478-533,A:554-610
O95831DB03147FAD4fdce4fdcB4B:128-261,B:399-475
O95831DB03147FAD4fdce4fdcB5B:262-398
O95831DB03147FAD4fdce4fdcB6B:476-537,B:560-610
O95831DB03147FAD4liie4liiA10A:478-533,A:554-611
O95831DB03147FAD4liie4liiA8A:263-400
O95831DB03147FAD4liie4liiA9A:125-262,A:400-477
O95831DB03147FAD5fmhe5fmhA1A:128-262,A:400-477
O95831DB03147FAD5fmhe5fmhA2A:263-400
O95831DB03147FAD5fmhe5fmhA3A:478-533,A:554-613
O95831DB03147FAD5fs6e5fs6A1A:264-400
O95831DB03147FAD5fs6e5fs6A2A:127-263,A:401-477
O95831DB03147FAD5fs6e5fs6A3A:478-521,A:559-617
O95831DB03147FAD5fs6e5fs6B1B:478-522,B:559-612
O95831DB03147FAD5fs6e5fs6B2B:126-263,B:401-477
O95831DB03147FAD5fs6e5fs6B3B:264-400
O95831DB03147FAD5fs7e5fs7A1A:264-400
O95831DB03147FAD5fs7e5fs7A2A:478-521,A:560-612
O95831DB03147FAD5fs7e5fs7A3A:126-263,A:401-477
O95831DB03147FAD5fs7e5fs7B1B:264-400
O95831DB03147FAD5fs7e5fs7B2B:478-521,B:560-613
O95831DB03147FAD5fs7e5fs7B3B:127-263,B:401-477
O95831DB03147FAD5fs8e5fs8A1A:478-539,A:560-611
O95831DB03147FAD5fs8e5fs8A2A:125-263,A:401-477
O95831DB03147FAD5fs8e5fs8A3A:264-400
O95831DB03147FAD5fs9e5fs9A1A:126-263,A:401-477
O95831DB03147FAD5fs9e5fs9A2A:264-400
O95831DB03147FAD5fs9e5fs9A3A:478-530,A:559-612
O95831DB03147FAD5fs9e5fs9B1B:126-263,B:401-477
O95831DB03147FAD5fs9e5fs9B2B:264-400
O95831DB03147FAD5fs9e5fs9B3B:478-530,B:558-617
O95831DB03147FAD5kvhe5kvhA1A:264-400
O95831DB03147FAD5kvhe5kvhA2A:126-263,A:401-477
O95831DB03147FAD5kvhe5kvhA3A:478-510,A:560-612
O95831DB03147FAD5kvhe5kvhB1B:264-400
O95831DB03147FAD5kvhe5kvhB2B:478-510,B:560-612
O95831DB03147FAD5kvhe5kvhB3B:126-263,B:401-477
O95831DB03147FAD5kvie5kviA1A:263-400
O95831DB03147FAD5kvie5kviA2A:478-533,A:554-619
O95831DB03147FAD5kvie5kviA3A:129-262,A:400-477
O95831DB03147FAD8d3ee8d3eA1A:264-400
O95831DB03147FAD8d3ee8d3eA2A:128-263,A:401-477
O95831DB03147FAD8d3ee8d3eA3A:478-509,A:561-611
O95831DB03147FAD8d3ee8d3eB1B:264-400
O95831DB03147FAD8d3ee8d3eB2B:478-510,B:561-611
O95831DB03147FAD8d3ee8d3eB3B:126-263,B:401-477
O95831DB03147FAD8d3ge8d3gA1A:264-400
O95831DB03147FAD8d3ge8d3gA2A:478-508,A:562-619
O95831DB03147FAD8d3ge8d3gA3A:128-263,A:401-477
O95831DB03147FAD8d3ge8d3gB1B:264-400
O95831DB03147FAD8d3ge8d3gB2B:129-263,B:401-477
O95831DB03147FAD8d3ge8d3gB3B:478-509,B:562-619
O95831DB03147FAD8d3he8d3hA1A:129-263,A:401-477
O95831DB03147FAD8d3he8d3hA2A:264-400
O95831DB03147FAD8d3he8d3hA3A:478-509,A:561-611
O95831DB03147FAD8d3he8d3hB1B:127-263,B:401-477
O95831DB03147FAD8d3he8d3hB2B:478-509,B:561-617
O95831DB03147FAD8d3he8d3hB3B:264-400
O95831DB03147FAD8d3ie8d3iA1A:264-400
O95831DB03147FAD8d3ie8d3iA2A:478-509,A:560-619
O95831DB03147FAD8d3ie8d3iA3A:127-263,A:401-477
O95831DB03147FAD8d3ie8d3iB1B:264-400
O95831DB03147FAD8d3ie8d3iB2B:478-509,B:562-611
O95831DB03147FAD8d3ie8d3iB3B:129-263,B:401-477
O95831DB03147FAD8d3je8d3jA1A:127-263,A:401-477
O95831DB03147FAD8d3je8d3jA2A:478-509,A:560-619
O95831DB03147FAD8d3je8d3jA3A:264-400
O95831DB03147FAD8d3je8d3jB1B:129-263,B:401-477
O95831DB03147FAD8d3je8d3jB2B:478-509,B:561-619
O95831DB03147FAD8d3je8d3jB3B:264-400
O95831DB03147FAD8d3ke8d3kA1A:264-400
O95831DB03147FAD8d3ke8d3kA2A:127-263,A:401-477
O95831DB03147FAD8d3ke8d3kA3A:478-509,A:560-619
O95831DB03147FAD8d3ke8d3kB1B:264-400
O95831DB03147FAD8d3ke8d3kB2B:478-509,B:561-619
O95831DB03147FAD8d3ke8d3kB3B:128-263,B:401-477
O95831DB03147FAD8d3ne8d3nA1A:264-400
O95831DB03147FAD8d3ne8d3nA2A:127-263,A:401-477
O95831DB03147FAD8d3ne8d3nA3A:478-509,A:561-619
O95831DB03147FAD8d3ne8d3nB1B:128-263,B:401-477
O95831DB03147FAD8d3ne8d3nB2B:478-509,B:562-619
O95831DB03147FAD8d3ne8d3nB3B:264-400
O95831DB03147FAD8d3oe8d3oA1A:127-263,A:401-477
O95831DB03147FAD8d3oe8d3oA2A:264-400
O95831DB03147FAD8d3oe8d3oA3A:478-509,A:561-619
O95831DB03147FAD8d3oe8d3oB1B:264-400
O95831DB03147FAD8d3oe8d3oB2B:128-263,B:401-477
O95831DB03147FAD8d3oe8d3oB3B:478-509,B:562-619