Attributes
UniProt ID
Protein Name
L-lactate dehydrogenase A chain
Ligand Name
2-{3-([1,1'-biphenyl]-3-yl)-5-(cyclopropylmethyl)-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ALJORCZKMBZYCR-UHFFFAOYSA-N
SMILES
c1ccc(cc1)c2cccc(c2)c3c(c(n(n3)c4nc(cs4)C(=O)O)CC5CC5)Cc6ccc(cc6)S(=O)(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5W8L
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Color Legend
Unassigned regionsLigand / hetero atomse5w8lA1e5w8lA2e5w8lB1e5w8lB2e5w8lC1e5w8lC2e5w8lD1e5w8lD2
ECOD domains from experimental PDB structures interacting with ligand 9YA
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P00338 | n/a | 9YA | 5w8l | e5w8lA1 | A:158-331 |
| P00338 | n/a | 9YA | 5w8l | e5w8lA2 | A:1-157 |
| P00338 | n/a | 9YA | 5w8l | e5w8lB1 | B:158-331 |
| P00338 | n/a | 9YA | 5w8l | e5w8lB2 | B:1-157 |
| P00338 | n/a | 9YA | 5w8l | e5w8lC1 | C:158-331 |
| P00338 | n/a | 9YA | 5w8l | e5w8lC2 | C:1-157 |
| P00338 | n/a | 9YA | 5w8l | e5w8lD1 | D:1-157 |
| P00338 | n/a | 9YA | 5w8l | e5w8lD2 | D:158-331 |