DrugDomain logoDrugDomain

Attributes

UniProt ID
P00338
Protein Name
L-lactate dehydrogenase A chain
Ligand Name
2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid
DrugBank ID
None
PDB Ligand Accession
P8M
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KTCLNOGFWLXRFB-UHFFFAOYSA-N
SMILES
c1cc(c(cc1Cc2c(n(nc2c3ccc(c(c3)C#CC4CCCC4)F)c5nc(cs5)C(=O)O)CC6CC6)F)S(=O)(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 6Q0D
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Color Legend
Unassigned regionsLigand / hetero atomse6q0dA1e6q0dA2e6q0dB1e6q0dB2e6q0dC1e6q0dC2e6q0dD1e6q0dD2e6q0dE1e6q0dE2e6q0dF1e6q0dF2
ECOD domains from experimental PDB structures interacting with ligand P8M
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00338n/aP8M6q0de6q0dA1A:158-331
P00338n/aP8M6q0de6q0dA2A:1-157
P00338n/aP8M6q0de6q0dB1B:1-157
P00338n/aP8M6q0de6q0dB2B:158-331
P00338n/aP8M6q0de6q0dC1C:158-331
P00338n/aP8M6q0de6q0dC2C:1-157
P00338n/aP8M6q0de6q0dD1D:158-331
P00338n/aP8M6q0de6q0dD2D:1-157
P00338n/aP8M6q0de6q0dE1E:1-157
P00338n/aP8M6q0de6q0dE2E:158-331
P00338n/aP8M6q0de6q0dF1F:158-331
P00338n/aP8M6q0de6q0dF2F:1-157