DrugDomain logoDrugDomain

(2S)-2-(5-{[(2-amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid

P00374 — Dihydrofolate reductase

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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
(2S)-2-(5-{[(2-amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid
DrugBank ID
None
PDB Ligand Accession
3TU
ChEMBL ID
CHEMBL1738740
PubChem ID
52914861
InChIKey
QPDXRVRRCIFNSL-HNNXBMFYSA-N
SMILES
c1cc(c2c(c1)sc3c2C(=O)NC(=N3)N)CNc4ccc5c(c4)CN(C5=O)C(CCC(=O)O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available