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5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE

P00374 Dihydrofolate reductase

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Attributes

UniProt ID
Protein Name
Dihydrofolate reductase
Ligand Name
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
PubChem ID
InChIKey
WKSAUQYGYAYLPV-UHFFFAOYSA-N
SMILES
CCc1c(c(nc(n1)N)N)c2ccc(cc2)Cl
Drug Action
inhibitor
Affinity Metrics
ki:8 nM
ic50:400 nM