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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
FOLIC ACID
DrugBank ID
DB00158
PDB Ligand Accession
FOL
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OVBPIULPVIDEAO-LBPRGKRZSA-N
SMILES
c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCc2cnc3c(n2)C(=O)N=C(N3)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 1DHF
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Color Legend
Unassigned regionsLigand / hetero atomse1dhfA1e1dhfB1
ECOD domains from experimental PDB structures interacting with ligand DB00158
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00374DB00158FOL1dhfe1dhfA1A:4-185
P00374DB00158FOL1dhfe1dhfB1B:4-185
P00374DB00158FOL1drfe1drfA1A:1-186
P00374DB00158FOL2w3be2w3bA1A:1-185
P00374DB00158FOL2w3be2w3bB1B:1-186
P00374DB00158FOL2w3me2w3mA1A:1-186
P00374DB00158FOL2w3me2w3mB1B:1-186
P00374DB00158FOL4kebe4kebB1B:1-186
P00374DB00158FOL4kfje4kfjB1B:1-186
P00374DB00158FOL4m6ke4m6kA1A:1-186
P00374DB00158FOL6vcje6vcjA1A:3-186
P00374DB00158FOL6vcje6vcjB1B:2-185
P00374DB00158FOL6vcje6vcjC1C:2-186
P00374DB00158FOL6vcje6vcjD1D:2-186
P00374DB00158FOL7esee7eseA1A:3-187