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Attributes

UniProt ID
Protein Name
Dihydrofolate reductase
Ligand Name
N-(4-{[(2,4-diaminopteridin-6-yl)methyl](hydroxymethyl)amino}benzene-1-carbonyl)-L-glutamic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KWWKVKGHDTULAH-ZDUSSCGKSA-N
SMILES
c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)N(Cc2cnc3c(n2)c(nc(n3)N)N)CO
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SDB
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Color Legend
Unassigned regionsLigand / hetero atomse5sdbA1e5sdbB1
ECOD domains from experimental PDB structures interacting with ligand G3V
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00374n/aG3V5sdbe5sdbA1A:2-187
P00374n/aG3V5sdbe5sdbB1B:2-187
P00374n/aG3V6dave6davA1A:2-187
P00374n/aG3V6dave6davB1B:2-187