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6-([5-QUINOLYLAMINO]METHYL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE

P00374 — Dihydrofolate reductase

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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
6-([5-QUINOLYLAMINO]METHYL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE
DrugBank ID
DB03351
PDB Ligand Accession
LIH
ChEMBL ID
CHEMBL151958
PubChem ID
446752
InChIKey
KMSATRJZEXNGDP-UHFFFAOYSA-N
SMILES
Cc1c(cnc2c1c(nc(n2)N)N)CNc3cccc4c3cccn4
Drug Action
n/a
Affinity Metrics
ic50:0.98 nM