DrugDomain logoDrugDomain

5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine

P00374 — Dihydrofolate reductase

← Back

Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
DrugBank ID
DB08234
PDB Ligand Accession
N22
ChEMBL ID
CHEMBL485961
PubChem ID
25058133
InChIKey
NNFDQABYXZBKRK-UHFFFAOYSA-N
SMILES
CCc1c(c(nc(n1)N)N)C#CCc2cc(ccc2OC)OC
Drug Action
n/a
Affinity Metrics
ic50:1280 nM