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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 1BOZ
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Color Legend
Unassigned regionsLigand / hetero atomse1bozA1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00374DB02338NDP1boze1bozA1A:1-186
P00374DB02338NDP1dlre1dlrA1A:1-186
P00374DB02338NDP1dlse1dlsA1A:1-186
P00374DB02338NDP1hfpe1hfpA1A:1-186
P00374DB02338NDP1hfqe1hfqA1A:1-186
P00374DB02338NDP1hfre1hfrA1A:1-186
P00374DB02338NDP1kmse1kmsA1A:2-186
P00374DB02338NDP1kmve1kmvA1A:1-186
P00374DB02338NDP1ohje1ohjA1A:1-186
P00374DB02338NDP1ohke1ohkA1A:1-186
P00374DB02338NDP1pd8e1pd8A1A:1-186
P00374DB02338NDP1u72e1u72A1A:1-186
P00374DB02338NDP1yhoe1yhoA1A:1-186
P00374DB02338NDP2c2se2c2sA1A:1-186
P00374DB02338NDP2c2se2c2sB1B:1-186
P00374DB02338NDP2c2te2c2tA1A:1-186
P00374DB02338NDP2c2te2c2tB1B:1-186
P00374DB02338NDP2w3ae2w3aA1A:1-186
P00374DB02338NDP2w3ae2w3aB1B:1-186
P00374DB02338NDP2w3be2w3bA1A:1-185
P00374DB02338NDP2w3be2w3bB1B:1-186
P00374DB02338NDP2w3me2w3mA1A:1-186
P00374DB02338NDP2w3me2w3mB1B:1-186
P00374DB02338NDP3f8ye3f8yA1A:1-186
P00374DB02338NDP3f8ze3f8zA1A:1-186
P00374DB02338NDP3f91e3f91A1A:1-186
P00374DB02338NDP3fs6e3fs6A1A:1-186
P00374DB02338NDP3ghce3ghcA1A:1-186
P00374DB02338NDP3ghve3ghvA1A:1-186
P00374DB02338NDP3ghwe3ghwA1A:1-186
P00374DB02338NDP3gi2e3gi2A1A:1-186
P00374DB02338NDP3gyfe3gyfA1A:1-186
P00374DB02338NDP3l3re3l3rA1A:1-186
P00374DB02338NDP3ntze3ntzA1A:1-186
P00374DB02338NDP3nu0e3nu0A1A:1-186
P00374DB02338NDP3nxoe3nxoA1A:1-186
P00374DB02338NDP3nxre3nxrA1A:1-186
P00374DB02338NDP3nxte3nxtA1A:1-186
P00374DB02338NDP3nxve3nxvA1A:1-186
P00374DB02338NDP3nxxe3nxxA1A:1-186
P00374DB02338NDP3nxye3nxyA1A:1-186
P00374DB02338NDP3nzde3nzdA1A:1-186
P00374DB02338NDP4ddre4ddrA1A:1-186
P00374DB02338NDP4kake4kakA1A:1-186
P00374DB02338NDP4kake4kakB1B:1-186
P00374DB02338NDP4kbne4kbnA1A:1-186
P00374DB02338NDP4kbne4kbnB1B:1-186
P00374DB02338NDP4kd7e4kd7A1A:1-186
P00374DB02338NDP4kd7e4kd7B1B:1-186
P00374DB02338NDP4kebe4kebA1A:1-186
P00374DB02338NDP4kebe4kebB1B:1-186
P00374DB02338NDP4kfje4kfjA1A:1-186
P00374DB02338NDP4kfje4kfjB1B:1-186
P00374DB02338NDP4m6je4m6jA1A:3-186
P00374DB02338NDP4qhve4qhvA1A:1-186
P00374DB02338NDP4qjce4qjcA1A:1-186
P00374DB02338NDP5hpbe5hpbA1A:1-186
P00374DB02338NDP5hqye5hqyA1A:1-186
P00374DB02338NDP5hqze5hqzA1A:1-186
P00374DB02338NDP5hsre5hsrA1A:1-186
P00374DB02338NDP5hsue5hsuA1A:1-186
P00374DB02338NDP5ht4e5ht4A1A:1-186
P00374DB02338NDP5ht5e5ht5A1A:1-186
P00374DB02338NDP5huie5huiA1A:1-186
P00374DB02338NDP5hvbe5hvbA1A:1-186
P00374DB02338NDP5hvee5hveA1A:1-186
P00374DB02338NDP6a7ce6a7cA1A:1-186
P00374DB02338NDP6a7ee6a7eA1A:1-186
P00374DB02338NDP6de4e6de4A1A:1-186
P00374DB02338NDP6de4e6de4B1B:1-186