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[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE

P00374 — Dihydrofolate reductase

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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
DrugBank ID
DB08406
PDB Ligand Accession
PMD
ChEMBL ID
CHEMBL301769
PubChem ID
446744
InChIKey
NXCCIJQEAKMFGW-UHFFFAOYSA-N
SMILES
c1ccc2c(c1)C=Cc3ccccc3N2Cc4cnc5c(n4)c(nc(n5)N)N
Drug Action
n/a
Affinity Metrics
ic50:12 nM