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N6-(2,5-DIMETHOXY-BENZYL)-N6-METHYL-PYRIDO[2,3-D]PYRIMIDINE-2,4,6-TRIAMINE

P00374 — Dihydrofolate reductase

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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
N6-(2,5-DIMETHOXY-BENZYL)-N6-METHYL-PYRIDO[2,3-D]PYRIMIDINE-2,4,6-TRIAMINE
DrugBank ID
DB02583
PDB Ligand Accession
PRD
ChEMBL ID
CHEMBL32113
PubChem ID
444617
InChIKey
HZTFNSCZLJLPEO-UHFFFAOYSA-N
SMILES
CN(Cc1cc(ccc1OC)OC)c2cc3c(nc(nc3nc2)N)N
Drug Action
n/a
Affinity Metrics
ic50:26 nM