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Attributes

UniProt ID
Protein Name
Dihydrofolate reductase
Ligand Name
TRIMETHOPRIM
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
IEDVJHCEMCRBQM-UHFFFAOYSA-N
SMILES
COc1cc(cc(c1OC)OC)Cc2cnc(nc2N)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 2W3A
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Color Legend
Unassigned regionsLigand / hetero atomse2w3aA1e2w3aB1
ECOD domains from experimental PDB structures interacting with ligand DB00440
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00374DB00440TOP2w3ae2w3aA1A:1-186
P00374DB00440TOP2w3ae2w3aB1B:1-186
P00374DB00440TOP3n0he3n0hA1A:1-186
P00374DB00440TOP3s3ve3s3vA1A:1-186