DrugDomain logoDrugDomain

4'-chloro-3'-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl][1,1'-biphenyl]-4-carboxamide

P00382 — Dihydrofolate reductase type 1

← Back

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 4SI

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 4SI

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00382n/a7reg4SIA201e7regA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00382n/a7reg4SIB201e7regB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1