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5-[(3S)-3-{7-[4-(aminomethyl)phenyl]-2H-1,3-benzodioxol-5-yl}but-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine

P00382 — Dihydrofolate reductase type 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 8MU

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 8MU

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00382n/a7rgj8MUA203e7rgjA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00382n/a7rgj8MUB204e7rgjB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1