DrugDomain logoDrugDomain

Attributes

UniProt ID
P00491
Protein Name
Purine nucleoside phosphorylase
Ligand Name
2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
DrugBank ID
None
PDB Ligand Accession
IM5
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GSPTUGDLYPMLCQ-SFYZADRCSA-N
SMILES
c1c(c2c([nH]1)C(=O)NC(=N2)N)CN3CC(C(C3)O)CO
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 3PHB
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse3phbE1e3phbQ1e3phbS1e3phbT1e3phbU1e3phbY1
ECOD domains from experimental PDB structures interacting with ligand IM5
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00491n/aIM53phbe3phbE1E:-2-285
P00491n/aIM53phbe3phbQ1Q:-1-285
P00491n/aIM53phbe3phbS1S:0-285
P00491n/aIM53phbe3phbT1T:-2-284
P00491n/aIM53phbe3phbU1U:3-287
P00491n/aIM53phbe3phbY1Y:1-285
P00491n/aIM54eare4earA1A:4-286
P00491n/aIM54eare4earB1B:2-288
P00491n/aIM54eare4earC1C:4-288
P00491n/aIM54eb8e4eb8A1A:-1-286
P00491n/aIM54eb8e4eb8B1B:-1-286
P00491n/aIM54eb8e4eb8C1C:4-286
P00491n/aIM55etje5etjA1A:-1-286
P00491n/aIM55etje5etjB1B:0-286
P00491n/aIM55etje5etjC1C:-1-286
P00491n/aIM55etje5etjD1D:-1-286
P00491n/aIM55etje5etjE1E:-1-286
P00491n/aIM55etje5etjF1F:-1-286
P00491n/aIM55ugfe5ugfA1A:1-286
P00491n/aIM55ugfe5ugfB1B:0-286
P00491n/aIM55ugfe5ugfC1C:-1-286
P00491n/aIM55ugfe5ugfD1D:1-286
P00491n/aIM55ugfe5ugfE1E:0-286
P00491n/aIM55ugfe5ugfF1F:0-286