Attributes
UniProt ID
Protein Name
Tyrosine-protein kinase ABL1
Ligand Name
N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ZBNZXTGUTAYRHI-UHFFFAOYSA-N
SMILES
Cc1cccc(c1NC(=O)c2cnc(s2)Nc3cc(nc(n3)C)N4CCN(CC4)CCO)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 2GQG
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Color Legend
Unassigned regionsLigand / hetero atomse2gqgA1e2gqgB1
ECOD domains from experimental PDB structures interacting with ligand DB01254
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P00519 | DB01254 | 1N1 | 2gqg | e2gqgA1 | A:223-500 |
| P00519 | DB01254 | 1N1 | 2gqg | e2gqgB1 | B:223-499 |
| P00519 | DB01254 | 1N1 | 4xey | e4xeyA1 | A:250-522 |
| P00519 | DB01254 | 1N1 | 4xey | e4xeyB1 | B:239-523 |
| P00519 | DB01254 | 1N1 | 7n9g | e7n9gA1 | A:252-517 |
| P00519 | DB01254 | 1N1 | 7n9g | e7n9gB1 | B:252-517 |
| P00519 | DB01254 | 1N1 | 7n9g | e7n9gC1 | C:253-518 |