Attributes
UniProt ID
Protein Name
Epidermal growth factor receptor
Ligand Name
N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin-3-yl]propanamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XWNKXCUQRQRAFF-GHMZBOCLSA-N
SMILES
CCC(=O)NC1CN(CC1F)c2nc(c3c(n2)n(cn3)C)Nc4cn(nc4OC)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5UGC
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Color Legend
Unassigned regionsLigand / hetero atomse5ugcA1
ECOD domains from experimental PDB structures interacting with ligand 8BS
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P00533 | n/a | 8BS | 5ugc | e5ugcA1 | A:702-985 |
| P00533 | n/a | 8BS | 6z4d | e6z4dA1 | A:701-984 |
| P00533 | n/a | 8BS | 6z4d | e6z4dB1 | B:700-984 |
| P00533 | n/a | 8BS | 7jxi | e7jxiA1 | A:700-985 |
| P00533 | n/a | 8BS | 7jxi | e7jxiB1 | B:702-1004 |
| P00533 | n/a | 8BS | 7jxi | e7jxiC1 | C:700-986 |
| P00533 | n/a | 8BS | 7jxi | e7jxiD1 | D:702-985 |
| P00533 | n/a | 8BS | 7jxk | e7jxkA1 | A:700-986 |
| P00533 | n/a | 8BS | 7jxk | e7jxkC1 | C:701-985 |
| P00533 | n/a | 8BS | 7jxk | e7jxkD1 | D:700-986 |
| P00533 | n/a | 8BS | 7jxk | e7jxkE1 | E:700-986 |
| P00533 | n/a | 8BS | 7jxk | e7jxkF1 | F:700-986 |