DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Epidermal growth factor receptor
Ligand Name
N-{trans-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl}propanamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
WVLWGBZNXIVAKC-YOCNBXQISA-N
SMILES
CCC(=O)NC1CCC(CC1)N2c3c(cnc(n3)Nc4ccc(c(c4)C)N5CCN(CC5)C)CN(C2=O)c6ccccc6Cl
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 5ZTO
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse5ztoA1
ECOD domains from experimental PDB structures interacting with ligand 9JO
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00533n/a9JO5ztoe5ztoA1A:697-1017
P00533n/a9JO6jrxe6jrxA1A:696-987,A:1009-1017