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Attributes

UniProt ID
P00533
Protein Name
Epidermal growth factor receptor
Ligand Name
(2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide
DrugBank ID
None
PDB Ligand Accession
JBJ
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VHQVOTINPRYDAO-AREMUKBSSA-N
SMILES
c1cc(ccc1c2ccc3c(c2)C(=O)N(C3)C(c4cc(ccc4O)F)C(=O)Nc5nccs5)N6CCNCC6
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 6DUK
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Color Legend
Unassigned regionsLigand / hetero atomse6dukA1e6dukB1e6dukC1e6dukD1e6dukE1e6dukF1
ECOD domains from experimental PDB structures interacting with ligand JBJ
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00533n/aJBJ6duke6dukA1A:701-1006
P00533n/aJBJ6duke6dukB1B:699-1007
P00533n/aJBJ6duke6dukC1C:699-1007
P00533n/aJBJ6duke6dukD1D:701-1007
P00533n/aJBJ6duke6dukE1E:698-1007
P00533n/aJBJ6duke6dukF1F:701-1009
P00533n/aJBJ7jxke7jxkA1A:700-986
P00533n/aJBJ7jxke7jxkC1C:701-985
P00533n/aJBJ7jxke7jxkD1D:700-986
P00533n/aJBJ7jxke7jxkE1E:700-986
P00533n/aJBJ7jxke7jxkF1F:700-986
P00533n/aJBJ7jxpe7jxpA1A:700-986
P00533n/aJBJ7jxpe7jxpB1B:700-986
P00533n/aJBJ7jxpe7jxpC1C:700-986
P00533n/aJBJ7jxpe7jxpD1D:700-986
P00533n/aJBJ7jxpe7jxpE1E:700-986
P00533n/aJBJ7jxpe7jxpF1F:700-986