Attributes
UniProt ID
Protein Name
Epidermal growth factor receptor
Ligand Name
~{N}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UHTBXBRYOKJTAN-UHFFFAOYSA-N
SMILES
CCC(=O)Nc1cc(c(cc1N(C)CCN(C)C)OC)Nc2nccc(n2)c3cn(c4c3cccc4)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6XL4
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Color Legend
Unassigned regionsLigand / hetero atomse6xl4A1e6xl4B1e6xl4C1e6xl4D1
ECOD domains from experimental PDB structures interacting with ligand Q6K
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P00533 | n/a | Q6K | 6xl4 | e6xl4A1 | A:700-1007 |
| P00533 | n/a | Q6K | 6xl4 | e6xl4B1 | B:700-1007 |
| P00533 | n/a | Q6K | 6xl4 | e6xl4D1 | D:700-1013 |
| P00533 | n/a | Q6K | 6z4b | e6z4bA1 | A:700-982 |
| P00533 | n/a | Q6K | 6z4b | e6z4bB1 | B:699-984 |
| P00533 | n/a | Q6K | 7lgs | e7lgsA1 | A:702-987 |
| P00533 | n/a | Q6K | 7lgs | e7lgsB1 | B:702-987 |
| P00533 | n/a | Q6K | 7lgs | e7lgsC1 | C:701-987 |
| P00533 | n/a | Q6K | 7lgs | e7lgsD1 | D:701-987 |