Attributes
UniProt ID
Protein Name
Epidermal growth factor receptor
Ligand Name
propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
CINKQTDSFCVDKO-UHFFFAOYSA-N
SMILES
CCC(=O)Nc1cc(c(cc1N(C)CCN(C)C)OC)Nc2ncc(c(n2)c3cn(c4c3cccc4)C)C(=O)OC(C)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 7A6K
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Color Legend
Unassigned regionsLigand / hetero atomse7a6kA1e7a6kB1e7a6kC1e7a6kD1
ECOD domains from experimental PDB structures interacting with ligand R28
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P00533 | n/a | R28 | 7a6k | e7a6kA1 | A:700-984 |
| P00533 | n/a | R28 | 7a6k | e7a6kB1 | B:700-982 |
| P00533 | n/a | R28 | 7a6k | e7a6kC1 | C:700-984 |
| P00533 | n/a | R28 | 7a6k | e7a6kD1 | D:702-984 |
| P00533 | n/a | R28 | 7b85 | e7b85A1 | A:697-1020 |
| P00533 | n/a | R28 | 7t4i | e7t4iA1 | A:697-1017 |
| P00533 | n/a | R28 | 7t4j | e7t4jA1 | A:701-987 |
| P00533 | n/a | R28 | 7t4j | e7t4jB1 | B:701-987 |
| P00533 | n/a | R28 | 8f1x | e8f1xA1 | A:696-1018 |