DrugDomain logoDrugDomain

N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-fluoro-5-hydroxybenzamide

P00533 — Epidermal growth factor receptor

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TOV

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TOV

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00533n/a6wa2TOVA1301e6wa2A1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
P00533n/a6wa2TOVB1202e6wa2B1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
P00533n/a6wa2TOVC1202e6wa2C1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
P00533n/a6wa2TOVD1301e6wa2D1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr