DrugDomain logoDrugDomain

Attributes

UniProt ID
P00533
Protein Name
Epidermal growth factor receptor
Ligand Name
(2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide
DrugBank ID
None
PDB Ligand Accession
VNS
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SYTVDTWRIZNVEW-MUUNZHRXSA-N
SMILES
CN1CCC(CC1)c2ccc(cc2)c3ccc4c(c3)C(=O)N(C4)C(c5cc(ccc5O)F)C(=O)Nc6nccs6
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 7JXQ
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Color Legend
Unassigned regionsLigand / hetero atomse7jxqA1e7jxqB1e7jxqC1e7jxqD1
ECOD domains from experimental PDB structures interacting with ligand VNS
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00533n/aVNS7jxqe7jxqA1A:700-986
P00533n/aVNS7jxqe7jxqB1B:701-985
P00533n/aVNS7jxqe7jxqC1C:700-986
P00533n/aVNS7jxqe7jxqD1D:700-986
P00533n/aVNS7jxwe7jxwA1A:700-986
P00533n/aVNS7jxwe7jxwB1B:700-986
P00533n/aVNS7jxwe7jxwC1C:700-986
P00533n/aVNS7jxwe7jxwD1D:700-986
P00533n/aVNS7k1he7k1hA1A:701-985
P00533n/aVNS7k1he7k1hB1B:701-986
P00533n/aVNS7k1he7k1hC1C:701-985
P00533n/aVNS7k1he7k1hD1D:701-985
P00533n/aVNS7k1he7k1hE1E:703-985
P00533n/aVNS7k1he7k1hF1F:701-985
P00533n/aVNS7k1ie7k1iA1A:700-985
P00533n/aVNS7lg8e7lg8A1A:702-1006
P00533n/aVNS7lg8e7lg8B1B:702-1002
P00533n/aVNS7lg8e7lg8C1C:703-1004
P00533n/aVNS7lg8e7lg8D1D:702-1003