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Attributes

UniProt ID
P00533
Protein Name
Epidermal growth factor receptor
Ligand Name
N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
DrugBank ID
DB09330
PDB Ligand Accession
YY3
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
DUYJMQONPNNFPI-UHFFFAOYSA-N
SMILES
Cn1cc(c2c1cccc2)c3ccnc(n3)Nc4cc(c(cc4OC)N(C)CCN(C)C)NC(=O)C=C
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 4ZAU
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Color Legend
Unassigned regionsLigand / hetero atomse4zauA1
ECOD domains from experimental PDB structures interacting with ligand DB09330
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P00533DB09330YY34zaue4zauA1A:698-984,A:1008-1017
P00533DB09330YY36jwle6jwlA1A:696-1020
P00533DB09330YY36jx4e6jx4A1A:696-1018
P00533DB09330YY36jxte6jxtA1A:697-984
P00533DB09330YY36lude6ludA1A:696-1018
P00533DB09330YY37jxme7jxmB1B:701-1012
P00533DB09330YY37jxpe7jxpC1C:700-986
P00533DB09330YY37jxpe7jxpE1E:700-986
P00533DB09330YY37jxwe7jxwA1A:700-986
P00533DB09330YY37jxwe7jxwB1B:700-986
P00533DB09330YY37jxwe7jxwC1C:700-986
P00533DB09330YY37jxwe7jxwD1D:700-986
P00533DB09330YY37k1he7k1hA1A:701-985
P00533DB09330YY37k1he7k1hB1B:701-986
P00533DB09330YY37k1he7k1hC1C:701-985
P00533DB09330YY37k1he7k1hD1D:701-985
P00533DB09330YY37k1he7k1hE1E:703-985
P00533DB09330YY37k1he7k1hF1F:701-985