DrugDomain logoDrugDomain

(1~{R},3~{S},5~{R})-~{N}2-(1-aminocarbonylindol-3-yl)-~{N}3-[3-(trifluoromethyloxy)phenyl]-2-azabicyclo[3.1.0]hexane-2,3-dicarboxamide

P00746 — Complement factor D

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 8RZ

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 8RZ

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00746n/a5naw8RZA301e5nawA1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin