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1-(2-{(2S)-2-[(6-bromopyridin-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

P00746 — Complement factor D

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand J55

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand J55

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00746n/a5tcaJ55A500e5tcaA1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55A500e5tcaC1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55B500e5tcaB1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55C302e5tcaC1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55D302e5tcaD1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55D302e5tcaE1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55E500e5tcaE1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55F500e5tcaD1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55F500e5tcaF1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin
P00746n/a5tcaJ55G500e5tcaG1cradle loop barrelRIFT-relatedFMN-binding split barrel 2Trypsin