NICKEL (II) ION

P00751 — Complement factor B

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand NI

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P00751	None	NI	000000245	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
P00751	None	NI	000023078	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin

Show other predicted domains (60)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1DLE	e1dleB2	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
1DLE	e1dleA2	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
1Q0P	e1q0pA1	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
1RRK	e1rrkA2	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
1RS0	e1rs0A2	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
1RTK	e1rtkA1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
1RTK	e1rtkA2	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
2OK5	e2ok5A9	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2ok5A8	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e2ok5A1	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2ok5A2	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2ok5A3	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
2WIN	e2winI4	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2winJ4	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2winK4	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2winL4	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2winI3	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e2winJ3	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e2winK3	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e2winL3	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
2XWB	e2xwbF9	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2xwbH9	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e2xwbF8	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e2xwbH8	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e2xwbF3	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2xwbF4	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2xwbF5	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2xwbH3	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2xwbH4	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e2xwbH5	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
3HRZ	e3hrzD4	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e3hrzD5	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e3hrzD3	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hrzD6	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hrzD7	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
3HS0	e3hs0I9	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e3hs0D4	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e3hs0I8	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e3hs0D5	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e3hs0I3	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hs0I4	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hs0I5	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hs0D3	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hs0D6	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
	e3hs0D7	389.1.2	EGF-like	EGF-related	Complement control module/SCR domain	Sushi
6QSW	e6qswAAA1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e6qswBBB1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e6qswCCC1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
6QSX	e6qsxAAA1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
6QSX	e6qsxBBB1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
6RAV	e6ravAAA1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
6RAV	e6ravBBB1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
6RUR	e6rurJ1	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e6rurL2	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e6rurJ2	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e6rurL1	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
6RUV	e6ruvJ2	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e6ruvL2	1.1.17	cradle loop barrel	RIFT-related	FMN-binding split barrel 2	Trypsin
	e6ruvJ1	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA
	e6ruvL1	2006.1.6	HAD domain-like	HAD domain-related	vWA-like	VWA

ECOD domains from experimental PDB structures interacting with ligand NI

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P00751	n/a	2xwj	NI	I	1742	e2xwjI11	HAD domain-like	HAD domain-related	vWA-like	VWA
P00751	n/a	2xwj	NI	J	1742	e2xwjJ8	HAD domain-like	HAD domain-related	vWA-like	VWA
P00751	n/a	2xwj	NI	K	1742	e2xwjK8	HAD domain-like	HAD domain-related	vWA-like	VWA
P00751	n/a	2xwj	NI	L	1742	e2xwjL10	HAD domain-like	HAD domain-related	vWA-like	VWA