[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate

P00918 — Carbonic anhydrase 2

Attributes

UniProt ID

Protein Name

Carbonic anhydrase 2

Ligand Name

[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

KJADKKWYZYXHBB-XBWDGYHZSA-N

SMILES

CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C

Drug Action

inhibitor

Affinity Metrics

ki:5 nM

ic50:5 nM

kd:13.8 nM