DrugDomain

Attributes

UniProt ID

P01116

Protein Name

GTPase KRas

Ligand Name

GUANOSINE-5'-DIPHOSPHATE

DrugBank ID

DB04315

PDB Ligand Accession

GDP

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

QGWNDRXFNXRZMB-UUOKFMHZSA-N

SMILES

c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*

Structure: 2MSC

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Color Legend

Unassigned regionsLigand / hetero atomse2mscA1e2mscB1e2mscC1

ECOD domains from experimental PDB structures interacting with ligand DB04315

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
P01116	DB04315	GDP	2msc	e2mscB1	B:1-185
P01116	DB04315	GDP	4dsu	e4dsuA1	A:0-179
P01116	DB04315	GDP	4epr	e4eprA1	A:1-166
P01116	DB04315	GDP	4ept	e4eptA1	A:0-161
P01116	DB04315	GDP	4epv	e4epvA1	A:0-161
P01116	DB04315	GDP	4epw	e4epwA1	A:0-161
P01116	DB04315	GDP	4epx	e4epxA1	A:0-161
P01116	DB04315	GDP	4epy	e4epyA1	A:0-161
P01116	DB04315	GDP	4l8g	e4l8gA1	A:1-167
P01116	DB04315	GDP	4ldj	e4ldjA1	A:0-169
P01116	DB04315	GDP	4lpk	e4lpkA1	A:1-166
P01116	DB04315	GDP	4lpk	e4lpkB1	B:1-166
P01116	DB04315	GDP	4lrw	e4lrwA1	A:2-167
P01116	DB04315	GDP	4lrw	e4lrwB1	B:2-167
P01116	DB04315	GDP	4luc	e4lucA1	A:1-168
P01116	DB04315	GDP	4luc	e4lucB1	B:1-168
P01116	DB04315	GDP	4lv6	e4lv6A1	A:1-168
P01116	DB04315	GDP	4lv6	e4lv6B1	B:1-167
P01116	DB04315	GDP	4lyf	e4lyfA1	A:1-167
P01116	DB04315	GDP	4lyf	e4lyfB1	B:1-167
P01116	DB04315	GDP	4lyf	e4lyfC1	C:2-167
P01116	DB04315	GDP	4lyh	e4lyhA1	A:1-168
P01116	DB04315	GDP	4lyh	e4lyhB1	B:1-169
P01116	DB04315	GDP	4lyh	e4lyhC1	C:1-168
P01116	DB04315	GDP	4lyj	e4lyjA1	A:2-167
P01116	DB04315	GDP	4m1o	e4m1oA1	A:1-167
P01116	DB04315	GDP	4m1o	e4m1oB1	B:1-168
P01116	DB04315	GDP	4m1o	e4m1oC1	C:1-167
P01116	DB04315	GDP	4m1s	e4m1sA1	A:1-167
P01116	DB04315	GDP	4m1s	e4m1sB1	B:1-168
P01116	DB04315	GDP	4m1s	e4m1sC1	C:1-167
P01116	DB04315	GDP	4m1t	e4m1tA1	A:1-168
P01116	DB04315	GDP	4m1t	e4m1tB1	B:1-168
P01116	DB04315	GDP	4m1t	e4m1tC1	C:1-168
P01116	DB04315	GDP	4m1w	e4m1wA1	A:1-168
P01116	DB04315	GDP	4m1w	e4m1wB1	B:1-168
P01116	DB04315	GDP	4m1w	e4m1wC1	C:1-167
P01116	DB04315	GDP	4m1y	e4m1yA1	A:1-168
P01116	DB04315	GDP	4m1y	e4m1yB1	B:1-169
P01116	DB04315	GDP	4m1y	e4m1yC1	C:1-167
P01116	DB04315	GDP	4m21	e4m21A1	A:1-167
P01116	DB04315	GDP	4m21	e4m21B1	B:1-168
P01116	DB04315	GDP	4m21	e4m21C1	C:2-167
P01116	DB04315	GDP	4m22	e4m22A1	A:1-168
P01116	DB04315	GDP	4m22	e4m22B1	B:2-167
P01116	DB04315	GDP	4m22	e4m22C1	C:2-168
P01116	DB04315	GDP	4obe	e4obeA1	A:1-169
P01116	DB04315	GDP	4obe	e4obeB1	B:0-169
P01116	DB04315	GDP	4pzy	e4pzyA1	A:0-169
P01116	DB04315	GDP	4pzy	e4pzyB1	B:0-169
P01116	DB04315	GDP	4pzz	e4pzzA1	A:0-169
P01116	DB04315	GDP	4q01	e4q01A1	A:1-166
P01116	DB04315	GDP	4q01	e4q01B1	B:1-169
P01116	DB04315	GDP	4q02	e4q02A1	A:0-169
P01116	DB04315	GDP	4q03	e4q03A1	A:0-169
P01116	DB04315	GDP	4ql3	e4ql3A1	A:0-169
P01116	DB04315	GDP	4tq9	e4tq9A1	A:0-168
P01116	DB04315	GDP	4tq9	e4tq9B1	B:0-168
P01116	DB04315	GDP	4tqa	e4tqaA1	A:0-168
P01116	DB04315	GDP	4tqa	e4tqaB1	B:0-168
P01116	DB04315	GDP	4wa7	e4wa7A1	A:0-167
P01116	DB04315	GDP	5f2e	e5f2eA1	A:0-167
P01116	DB04315	GDP	5mlb	e5mlbA1	A:1-165
P01116	DB04315	GDP	5mlb	e5mlbC1	C:1-165
P01116	DB04315	GDP	5mlb	e5mlbE1	E:1-165
P01116	DB04315	GDP	5mlb	e5mlbG1	G:1-164
P01116	DB04315	GDP	5o2s	e5o2sA1	A:1-165
P01116	DB04315	GDP	5o2s	e5o2sC1	C:1-165
P01116	DB04315	GDP	5o2s	e5o2sE1	E:1-165
P01116	DB04315	GDP	5o2s	e5o2sG1	G:1-164
P01116	DB04315	GDP	5tar	e5tarA1	A:1-185
P01116	DB04315	GDP	5tb5	e5tb5A1	A:1-185
P01116	DB04315	GDP	5tb5	e5tb5C1	C:2-185
P01116	DB04315	GDP	5uk9	e5uk9A1	A:1-166
P01116	DB04315	GDP	5uqw	e5uqwA1	A:1-168
P01116	DB04315	GDP	5uqw	e5uqwB1	B:1-167
P01116	DB04315	GDP	5us4	e5us4A1	A:1-169
P01116	DB04315	GDP	5us4	e5us4B1	B:1-169
P01116	DB04315	GDP	5v6s	e5v6sA1	A:0-169
P01116	DB04315	GDP	5v6v	e5v6vA1	A:2-167
P01116	DB04315	GDP	5v6v	e5v6vB1	B:2-168
P01116	DB04315	GDP	5v71	e5v71A1	A:0-168
P01116	DB04315	GDP	5v71	e5v71B1	B:0-168
P01116	DB04315	GDP	5v71	e5v71C1	C:0-168
P01116	DB04315	GDP	5v71	e5v71D1	D:0-168
P01116	DB04315	GDP	5v71	e5v71E1	E:0-168
P01116	DB04315	GDP	5v71	e5v71F1	F:0-168
P01116	DB04315	GDP	5v9l	e5v9lA1	A:0-168
P01116	DB04315	GDP	5v9l	e5v9lB1	B:0-168
P01116	DB04315	GDP	5v9l	e5v9lC1	C:0-168
P01116	DB04315	GDP	5v9o	e5v9oA1	A:1-168
P01116	DB04315	GDP	5v9u	e5v9uA1	A:1-169
P01116	DB04315	GDP	5v9u	e5v9uB1	B:2-168
P01116	DB04315	GDP	5vbm	e5vbmA1	A:0-169
P01116	DB04315	GDP	5vp7	e5vp7A1	A:0-169
P01116	DB04315	GDP	5vp7	e5vp7F1	F:0-169
P01116	DB04315	GDP	5vq0	e5vq0A1	A:1-169
P01116	DB04315	GDP	5vq0	e5vq0B1	B:1-169
P01116	DB04315	GDP	5vq1	e5vq1A1	A:0-169
P01116	DB04315	GDP	5vq1	e5vq1B1	B:0-169
P01116	DB04315	GDP	5vq8	e5vq8A1	A:0-168
P01116	DB04315	GDP	5vq8	e5vq8B1	B:0-168
P01116	DB04315	GDP	5w22	e5w22A1	A:0-169
P01116	DB04315	GDP	5w22	e5w22B1	B:0-169
P01116	DB04315	GDP	5wha	e5whaA1	A:2-166
P01116	DB04315	GDP	5wha	e5whaD1	D:1-166
P01116	DB04315	GDP	5wha	e5whaG1	G:2-166
P01116	DB04315	GDP	5wha	e5whaJ1	J:2-165
P01116	DB04315	GDP	5whb	e5whbA1	A:1-166
P01116	DB04315	GDP	5whb	e5whbD1	D:1-166
P01116	DB04315	GDP	5whb	e5whbG1	G:2-166
P01116	DB04315	GDP	5whb	e5whbJ1	J:1-166
P01116	DB04315	GDP	5whd	e5whdA1	A:1-165
P01116	DB04315	GDP	5whd	e5whdB1	B:1-166
P01116	DB04315	GDP	5whd	e5whdC1	C:1-166
P01116	DB04315	GDP	5whd	e5whdD1	D:1-166
P01116	DB04315	GDP	5xco	e5xcoA1	A:0-169
P01116	DB04315	GDP	5yxz	e5yxzA1	A:0-169
P01116	DB04315	GDP	5yy1	e5yy1A1	A:0-169
P01116	DB04315	GDP	6ark	e6arkA1	A:0-169
P01116	DB04315	GDP	6asa	e6asaA1	A:1-168
P01116	DB04315	GDP	6ase	e6aseA1	A:1-169
P01116	DB04315	GDP	6b0v	e6b0vA1	A:1-167
P01116	DB04315	GDP	6b0v	e6b0vB1	B:1-167
P01116	DB04315	GDP	6b0y	e6b0yA1	A:1-168
P01116	DB04315	GDP	6b0y	e6b0yB1	B:2-168
P01116	DB04315	GDP	6bof	e6bofA1	A:2-169
P01116	DB04315	GDP	6bof	e6bofB1	B:2-169
P01116	DB04315	GDP	6e6g	e6e6gA1	A:1-166
P01116	DB04315	GDP	6h46	e6h46A1	A:-1-166
P01116	DB04315	GDP	6m9w	e6m9wA1	A:2-169
P01116	DB04315	GDP	6mbt	e6mbtA1	A:0-169
P01116	DB04315	GDP	6mbt	e6mbtB1	B:0-169
P01116	DB04315	GDP	6mbu	e6mbuA1	A:0-168
P01116	DB04315	GDP	6mbu	e6mbuB1	B:0-168
P01116	DB04315	GDP	6mqg	e6mqgA1	A:3-169
P01116	DB04315	GDP	6mqn	e6mqnA1	A:1-168
P01116	DB04315	GDP	6mqn	e6mqnB1	B:1-169
P01116	DB04315	GDP	6mqn	e6mqnC1	C:1-169
P01116	DB04315	GDP	6ms9	e6ms9A1	A:1-168
P01116	DB04315	GDP	6ms9	e6ms9B1	B:1-169
P01116	DB04315	GDP	6ms9	e6ms9C1	C:1-169
P01116	DB04315	GDP	6n2j	e6n2jA1	A:2-169
P01116	DB04315	GDP	6n2k	e6n2kA1	A:1-169
P01116	DB04315	GDP	6oim	e6oimA1	A:0-169
P01116	DB04315	GDP	6p0z	e6p0zA1	A:2-168
P01116	DB04315	GDP	6p0z	e6p0zB1	B:2-168
P01116	DB04315	GDP	6p8w	e6p8wA1	A:0-168
P01116	DB04315	GDP	6p8w	e6p8wB1	B:0-167
P01116	DB04315	GDP	6p8x	e6p8xA1	A:2-167
P01116	DB04315	GDP	6p8x	e6p8xB1	B:2-167
P01116	DB04315	GDP	6p8x	e6p8xC1	C:1-167
P01116	DB04315	GDP	6p8x	e6p8xD1	D:1-167
P01116	DB04315	GDP	6p8y	e6p8yA1	A:1-166
P01116	DB04315	GDP	6p8y	e6p8yB1	B:0-168
P01116	DB04315	GDP	6p8z	e6p8zA1	A:0-168
P01116	DB04315	GDP	6p8z	e6p8zB1	B:2-167
P01116	DB04315	GDP	6pgo	e6pgoA1	A:1-167
P01116	DB04315	GDP	6pgo	e6pgoB1	B:1-169
P01116	DB04315	GDP	6pgp	e6pgpA1	A:1-169
P01116	DB04315	GDP	6pgp	e6pgpB1	B:1-169
P01116	DB04315	GDP	6pq3	e6pq3A1	A:1-177
P01116	DB04315	GDP	6t5b	e6t5bA1	A:0-169
P01116	DB04315	GDP	6t5v	e6t5vA1	A:1-169
P01116	DB04315	GDP	6tam	e6tamA1	A:0-169
P01116	DB04315	GDP	6tan	e6tanA1	A:0-169
P01116	DB04315	GDP	6usx	e6usxA1	A:1-167
P01116	DB04315	GDP	6usx	e6usxB1	B:0-168
P01116	DB04315	GDP	6usz	e6uszA1	A:1-169
P01116	DB04315	GDP	6ut0	e6ut0A1	A:1-169
P01116	DB04315	GDP	6ut0	e6ut0B1	B:0-167
P01116	DB04315	GDP	6ut0	e6ut0C1	C:0-169
P01116	DB04315	GDP	6ut0	e6ut0D1	D:0-169
P01116	DB04315	GDP	6v5l	e6v5lA1	A:1-169
P01116	DB04315	GDP	6w4f	e6w4fB1	B:2-184
P01116	DB04315	GDP	6w4f	e6w4fC1	C:2-184
P01116	DB04315	GDP	6ws2	e6ws2A1	A:0-169
P01116	DB04315	GDP	6ws2	e6ws2B1	B:0-168
P01116	DB04315	GDP	6ws2	e6ws2C1	C:0-168
P01116	DB04315	GDP	6ws2	e6ws2D1	D:0-167
P01116	DB04315	GDP	6ws4	e6ws4A1	A:0-168
P01116	DB04315	GDP	6ws4	e6ws4B1	B:0-168
P01116	DB04315	GDP	6ws4	e6ws4C1	C:0-168
P01116	DB04315	GDP	6ws4	e6ws4D1	D:0-168
P01116	DB04315	GDP	6yr8	e6yr8A1	A:-1-166
P01116	DB04315	GDP	6yxw	e6yxwA1	A:2-167
P01116	DB04315	GDP	6yxw	e6yxwC1	C:1-167
P01116	DB04315	GDP	6zl5	e6zl5A1	A:0-167
P01116	DB04315	GDP	7a1x	e7a1xA1	A:0-169
P01116	DB04315	GDP	7a1y	e7a1yA1	A:1-169
P01116	DB04315	GDP	7acq	e7acqA1	A:1-167
P01116	DB04315	GDP	7acq	e7acqB1	B:1-167
P01116	DB04315	GDP	7acq	e7acqC1	C:1-167
P01116	DB04315	GDP	7c40	e7c40A1	A:1-168
P01116	DB04315	GDP	7c41	e7c41A1	A:1-168
P01116	DB04315	GDP	7c41	e7c41G1	G:1-168
P01116	DB04315	GDP	7c41	e7c41J1	J:1-168
P01116	DB04315	GDP	7c41	e7c41M1	M:1-168
P01116	DB04315	GDP	7ew9	e7ew9A1	A:1-168
P01116	DB04315	GDP	7ew9	e7ew9B1	B:0-168
P01116	DB04315	GDP	7ew9	e7ew9C1	C:1-168
P01116	DB04315	GDP	7ewa	e7ewaA1	A:0-168
P01116	DB04315	GDP	7ewb	e7ewbA1	A:0-168
P01116	DB04315	GDP	7kmr	e7kmrA1	A:2-172
P01116	DB04315	GDP	7lgi	e7lgiA1	A:1-169
P01116	DB04315	GDP	7mqu	e7mquA1	A:1-169
P01116	DB04315	GDP	7ny8	e7ny8A1	A:0-167
P01116	DB04315	GDP	7ny8	e7ny8B1	B:0-166
P01116	DB04315	GDP	7o70	e7o70A1	A:0-167
P01116	DB04315	GDP	7o70	e7o70D1	D:0-167
P01116	DB04315	GDP	7oo7	e7oo7A1	A:0-167
P01116	DB04315	GDP	7oo7	e7oo7D1	D:0-167
P01116	DB04315	GDP	7q9u	e7q9uAAA1	AAA:2-184
P01116	DB04315	GDP	7q9u	e7q9uBBB1	BBB:2-184
P01116	DB04315	GDP	7r0m	e7r0mA1	A:1-168
P01116	DB04315	GDP	7r0m	e7r0mB1	B:1-168
P01116	DB04315	GDP	7r0n	e7r0nA1	A:0-169
P01116	DB04315	GDP	7r0q	e7r0qA1	A:1-168
P01116	DB04315	GDP	7r0q	e7r0qB1	B:1-168
P01116	DB04315	GDP	7rp2	e7rp2A1	A:0-169
P01116	DB04315	GDP	7rp4	e7rp4A1	A:1-169
P01116	DB04315	GDP	7rp4	e7rp4B1	B:1-169
P01116	DB04315	GDP	7t47	e7t47A1	A:1-169
P01116	DB04315	GDP	7tle	e7tleA1	A:1-169
P01116	DB04315	GDP	7tlg	e7tlgA1	A:0-169
P01116	DB04315	GDP	7tlg	e7tlgB1	B:0-169
P01116	DB04315	GDP	7tlk	e7tlkA1	A:1-167
P01116	DB04315	GDP	7tlk	e7tlkB1	B:1-167
P01116	DB04315	GDP	7u8h	e7u8hA1	A:0-168
P01116	DB04315	GDP	7u8h	e7u8hB1	B:0-167
P01116	DB04315	GDP	7u8h	e7u8hC1	C:0-166
P01116	DB04315	GDP	7u8h	e7u8hD1	D:1-168
P01116	DB04315	GDP	7yuz	e7yuzA1	A:1-170
P01116	DB04315	GDP	7yv1	e7yv1A1	A:1-169
P01116	DB04315	GDP	8afb	e8afbA1	A:2-165
P01116	DB04315	GDP	8afc	e8afcA1	A:1-169
P01116	DB04315	GDP	8afc	e8afcB1	B:2-168
P01116	DB04315	GDP	8afd	e8afdA1	A:0-166
P01116	DB04315	GDP	8afd	e8afdB1	B:0-166
P01116	DB04315	GDP	8afd	e8afdC1	C:0-167
P01116	DB04315	GDP	8afd	e8afdD1	D:0-166
P01116	DB04315	GDP	8aq5	e8aq5A1	A:1-167
P01116	DB04315	GDP	8aq7	e8aq7A1	A:1-168
P01116	DB04315	GDP	8aq7	e8aq7B1	B:1-167
P01116	DB04315	GDP	8azr	e8azrA1	A:0-167
P01116	DB04315	GDP	8azv	e8azvA1	A:0-167
P01116	DB04315	GDP	8azx	e8azxA1	A:0-169
P01116	DB04315	GDP	8azy	e8azyA1	A:0-169
P01116	DB04315	GDP	8azz	e8azzA1	A:0-167
P01116	DB04315	GDP	8b00	e8b00A1	A:0-167
P01116	DB04315	GDP	8b6i	e8b6iA1	A:0-167
P01116	DB04315	GDP	8b6i	e8b6iB1	B:0-167
P01116	DB04315	GDP	8b78	e8b78A1	A:0-167
P01116	DB04315	GDP	8dni	e8dniA1	A:0-169
P01116	DB04315	GDP	8ecr	e8ecrA1	A:1-171
P01116	DB04315	GDP	8ecr	e8ecrB1	B:1-170
P01116	DB04315	GDP	8edy	e8edyA1	A:2-171
P01116	DB04315	GDP	8eer	e8eerA1	A:3-171
P01116	DB04315	GDP	8ezg	e8ezgA1	A:1-168
P01116	DB04315	GDP	8fmj	e8fmjA1	A:0-169
P01116	DB04315	GDP	8fmk	e8fmkA1	A:-6-169
P01116	DB04315	GDP	8g42	e8g42B1	B:1-165
P01116	DB04315	GDP	8g47	e8g47B1	B:1-168
P01116	DB04315	GDP	8g4f	e8g4fB1	B:1-165
P01116	DB04315	GDP	8g4h	e8g4hB1	B:1-168
P01116	DB04315	GDP	8jjs	e8jjsA1	A:1-169
P01116	DB04315	GDP	8onv	e8onvA1	A:0-168
P01116	DB04315	GDP	8stm	e8stmA1	A:0-168
P01116	DB04315	GDP	8stm	e8stmB1	B:0-168
P01116	DB04315	GDP	8stm	e8stmC1	C:0-168
P01116	DB04315	GDP	8stm	e8stmD1	D:0-168
P01116	DB04315	GDP	8stn	e8stnA1	A:2-168
P01116	DB04315	GDP	8stn	e8stnB1	B:1-168
P01116	DB04315	GDP	8txe	e8txeA1	A:0-169
P01116	DB04315	GDP	8txe	e8txeB1	B:0-169
P01116	DB04315	GDP	8txg	e8txgA1	A:0-169
P01116	DB04315	GDP	8txh	e8txhA1	A:0-169
P01116	DB04315	GDP	8txh	e8txhB1	B:0-169