1-{4-[2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one
P01116 — GTPase KRas
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand M1R
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand M1R
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P01116 | n/a | 6usx | M1R | A | 203 | e6usxA1 | P-loop domains-like | P-loop domains-related | P-loop containing nucleoside triphosphate hydrolases | Ras |
| P01116 | n/a | 6usx | M1R | A | 203 | e6usxB1 | P-loop domains-like | P-loop domains-related | P-loop containing nucleoside triphosphate hydrolases | Ras |
| P01116 | n/a | 6usx | M1R | B | 203 | e6usxA1 | P-loop domains-like | P-loop domains-related | P-loop containing nucleoside triphosphate hydrolases | Ras |
| P01116 | n/a | 6usx | M1R | B | 203 | e6usxB1 | P-loop domains-like | P-loop domains-related | P-loop containing nucleoside triphosphate hydrolases | Ras |